Comparison of differential Pavlovian conditioning in whole animals and physiological preparations of Pleurobranchaea: implications of motor pattern variability

Journal of Neurobiology
G J Mpitsos, C S Cohan

Abstract

The present study compares differential Pavlovian conditioning in whole animals with the behavior of the same animals during electrophysiological recording. Untrained specimens of the sea slug Pleurobranchaea did not discriminate between two appetitive stimuli, one derived from an extract of beer (Sbr) and the other from a homogenate of squid muscle (Ssq). When animals received Sbr as the CS+ and Ssq as the CS- in a single day of five-trial, differential Pavlovian conditioning they learned to avoid selectively the Sbr but continued to exhibit appetitive responses to Ssq. Quantitative measures show that there was over a 1000-fold increase in the thresholds of the proboscis extension and bite-strike responses, many animals ceased all feeding behavior, and exhibited withdrawal responses to Sbr. We examined the behavior of the same trained animals immediately before preparing them for physiological recording and during the recording session. There was a close one-to-one relationship between these behavioral observations, showing that the qualitative and quantitative features of whole-animal Pavlovian conditioning persist into the physiological preparations. Unexpectedly, motor patterns from untrained preparations showed considerabl...Continue Reading

References

Feb 3, 1978·Science·G J MpitsosA D McClellan
Jan 1, 1986·Annual Review of Neuroscience·T J Carew, C L Sahley
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
Jan 1, 1974·Journal of Neurobiology·R M Lee, R J Liegeois
Nov 1, 1984·Journal of Neurobiology·S Sombati, G Hoyle
Oct 29, 1982·Science·E R Kandel, J H Schwartz
Apr 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·J J Hopfield
Oct 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·A D MurphyW K Stell

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Citations

Sep 1, 1988·Brain Research Bulletin·G J MpitsosS O Soinila
Sep 1, 1988·Brain Research Bulletin·G J MpitsosH C Creech
Mar 25, 1998·Neuroreport·K L GainutdinovT H Gainutdinova
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan

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