Comparison of Duke Activity Status Index with cardiopulmonary exercise testing in cancer patients

Journal of Anesthesia
Michael H-G LiBernhard Riedel

Abstract

The Duke Activity Status Index (DASI), a patient-administered questionnaire, is used to quantify functional capacity in patients undergoing cancer surgery. This retrospective cohort study assessed whether the DASI was accurate in predicting peak oxygen consumption (pVO2) that was objectively measured using cardiopulmonary exercise testing (CPET) in 43 consecutive patients scheduled for elective major cancer surgery at a tertiary cancer centre. The primary outcome measured the limits of agreement between DASI-predicted pVO2 and actual measured pVO2. The study population was elderly (median 63 years, interquartile range 18), 58% were male, with the majority having intraabdominal cancer surgery. Although the DASI scores were statistically related to the measured pVO2 (N = 43, adjusted R2 = 0.20, p = 0.002), both the bias (8 ml kg- 1 min- 1) and 95% limits of agreement (19.5 to - 3.4 ml kg- 1 min- 1) between the predicted and measured pVO2 were large. Using some of the individual components, recalibrating the intercept and regression coefficient of the total DASI score did not substantially improve its ability to predict the measured pVO2. In summary, both the limits of agreement and bias between the measured and DASI-predicted pVO...Continue Reading

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Citations

Mar 8, 2019·Journal of Hospice and Palliative Nursing : JHPN : the Official Journal of the Hospice and Palliative Nurses Association·Mee Ok LeeJinShil Kim
Jan 30, 2019·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Michael H-G LiBernhard Riedel
Dec 1, 2020·International Anesthesiology Clinics·Paul S Richman, Deborah C Richman

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