Comparison of dynamic and passive measurements of respiratory mechanics in ventilated newborn infants

Pediatric Pulmonology
A KugelmanM Durand

Abstract

Pulmonary mechanics may differ in intubated and ventilated infants depending on whether they are measured by a dynamic or passive method. The objective of this study was to compare respiratory mechanics measured by a dynamic technique with those obtained by a single-breath occlusion technique in ventilated newborn infants. Thirty-one preterm and 15 term infants (mean +/- SD: gestational age, 29.3 +/- 2.3 and 39.5 +/- 1.4 weeks; birth weight, 1.2 +/- 0.5 and 3.4 +/- 0.4 kg; postnatal age, 12 +/- 13 and 5 +/- 4 days, respectively) were studied. Flows were measured through a pneumotachometer placed between the endotracheal tube and the ventilator circuit: tidal volume by integration of flow, and airway pressure directly with a pressure transducer. Airway occlusion was performed with a Neonatal Occlusion Valve (Bicore pulmonary monitor) at the end of inspiration, and the following relaxed exhalation was analyzed to give passive respiratory system compliance (Crs) and resistance (Rrs). These values were compared with dynamic respiratory system compliance (Cdyn) and dynamic expiratory resistance (Re) obtained with the PEDS system (P) within 1 hour, without an esophageal balloon and on the same ventilator settings. Dynamic respiratory...Continue Reading

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Citations

Sep 28, 2001·Medical Engineering & Physics·M L Costantino, G B Fiore
Nov 10, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Vincent RigoJacques Rigo
Mar 31, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Roland HentschelJosef Guttmann
Jun 12, 2010·Computer Methods and Programs in Biomedicine·Ashwath SundaresanGeoffrey M Shaw
Jul 28, 2005·Respiratory Physiology & Neurobiology·Peter B Frappell, Peter M MacFarlane
Mar 25, 2019·Pediatrics and Neonatology·Eimei HaradaOsuke Iwata
Dec 20, 2005·British Journal of Anaesthesia·G MolsJ Guttmann

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