Comparison of endoscopic submucosal dissection with surgical gastrectomy for early gastric cancer: An updated meta-analysis

World Journal of Gastrointestinal Oncology
Hua LiLi Zeng

Abstract

There are several surgical options for treating early gastric cancers (EGCs), such as endoscopic resection, laparoscopic or open gastrectomy with D1 or D2 lymphadenectomy. Endoscopic resection for EGC with low risk of lymph node metastasis has been widely accepted as a therapeutic alternative. The role of endoscopic submucosal dissection (ESD) in treating EGC is not well established, especially when compared with resection surgery cases in a long-term follow-up scope. To compare the safety and efficacy of the short- and long-term outcomes between ESD and resection surgery. We searched the databases of PubMed, EMBASE, Web of Science, and the Cochrane Library from January 1990 to June 2018, enrolling studies reporting short- or long-term outcomes of ESD in comparison with resection surgery for EGC. The quality of the studies was assessed by the Newcastle-Ottawa Quality Assessment Scale. Stata software (version 12.0) was used for the analysis. Pooling analysis was conducted using either fixed- or random-effects models depending on heterogeneity across studies. Fourteen studies comprising 5112 patients were eligible for analysis (2402 for EGC and 2710 for radical surgery). Our meta-analysis demonstrated that the ESD approach showed...Continue Reading

References

Dec 5, 2006·Gastrointestinal Endoscopy·Shiro OkaKazuaki Chayama
Mar 1, 2008·The Lancet Oncology·Wai K LeungUNKNOWN Asia Pacific Working Group on Gastric Cancer
May 17, 2011·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·UNKNOWN Japanese Gastric Cancer Association
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Oct 21, 2017·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Sunpyo LeeHwoon-Yong Jung

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Citations

May 13, 2020·Expert Review of Gastroenterology & Hepatology·Yuyong TanDeliang Liu
Feb 21, 2021·Gastroenterología y hepatología·Glòria Fernández-EsparrachUNKNOWN en representación de la Asociación Española de Gastroenterología, la Sociedad Española de Endoscopia Digestiva y la Sociedad
May 4, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Yoon Jung OhKeun Won Ryu
Jun 13, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jing YangTianye Niu

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Methods Mentioned

BETA
dissection
surgical resection

Software Mentioned

Stata

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