Comparison of entropy and bispectral index during propofol and fentanyl sedation in monitored anaesthesia care

The Journal of International Medical Research
Canan BalciRemziye Sivaci

Abstract

Comparison of entropy (state entropy [SE] and response entropy [RE]) with the bispectral index (BIS) during propofol sedation in monitored anaesthesia care (MAC) was carried out in patients undergoing hand surgery. Thirty candidates for elective hand surgery were pre-medicated with midazolam 0.06 mg/kg and atropine 0.01 mg/kg. Sedation was induced with intravenous propofol and fentanyl was also administered. The Modified Observer's Assessment of Alertness/Sedation Scale (MOAA/S) was used to determine sedation level and pain was maintained at < 4 on a 0 - 10 verbal rating scale. The BIS, entropy, MOAA/S and pain values were recorded before initiation of sedation (control), during initiation of sedation, during surgery, and for 30 min after the end of surgery and anaesthesia. On initiation of sedation, entropy decreased more rapidly than BIS. At 10 min after initiation of sedation, the mean +/- SD values for MOAA/S, BIS, RE and SE were 3.00 +/- 0.36, 85.45 +/- 0.15, 74.00 +/- 0.60 and 72.02 +/- 0.12, respectively. During recovery, BIS and RE and SE increased in parallel with MOAA/S. It is concluded that entropy monitoring is as reliable as BIS monitoring in MAC.

References

Oct 20, 1998·Anesthesiology·I J Rampil
Jun 9, 1999·Anesthesiology·T W SchniderE J Youngs
Mar 29, 2000·Anesthesia and Analgesia·S BadrinathA D Ivankovich
Dec 23, 2003·Anaesthesia·R E AndersonJan Jakobsson
Mar 5, 2004·Acta Anaesthesiologica Scandinavica·H Viertiö-OjaP Meriläinen
Mar 23, 2005·Anesthesia and Analgesia·Roy SotoRobert A Smith

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Citations

Jan 26, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sameh M Ragab, Maher Z Hassanin
Nov 3, 2010·Current Opinion in Anaesthesiology·Marko M SahinovicMichel M R F Struys
Apr 3, 2012·Anesthesia and Analgesia·Paul F WhiteGabriella Bettelli
Aug 16, 2017·Drugs & Aging·Xuezhao CaoHong Ma
Nov 6, 2010·Current Opinion in Anaesthesiology
Mar 10, 2011·Current Opinion in Anaesthesiology

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