Comparison of esophageal motility in gastroesophageal reflux disease with and without globus sensation

Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva
Yuming TangWeiyan Yao

Abstract

This study aimed to compare the esophageal motility between gastroesophageal reflux disease (GERD) patients with typical symptoms but without globus sensation and GERD patients only with globus symptoms. A total of 57 consecutive GERD patients diagnosed by endoscopy or by 24-hour pH monitoring between May 2013 and September 2015 were included retrospectively into the study. The patients were grouped based on the presence or absence of globus. Thirty patients presented with typical reflux symptoms but without globus were assigned to the typical GERD group and 27 patients only with globus symptom were assigned to the globus GERD group. All patients underwent esophageal high resolution manometry (HRM) and the differences in esophageal motility between the two groups were analyzed. The globus GERD group showed a significantly greater lower esophageal sphincter (LES) length, LES basal pressure and upper esophageal sphincter (UES) residual pressure than that of the typical GERD group (3.47 ± 0.76 vs. 2.65 ± 0.62 cm, 21.71 ± 9.68 vs. 16.04 ± 8.49 mmHg, 7.30 ± 4.42 vs. 4.12 ± 2.92 mmHg, all p < 0.05). There was no significant difference between the two groups in terms of the distal wave amplitude, mean wave duration, distal contractile...Continue Reading

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Citations

Feb 1, 2020·Journal of Gastroenterology and Hepatology·Songfeng ChenYinglian Xiao
Sep 18, 2018·Journal of Clinical Gastroenterology·José Tawil, Ronnie Fass
Apr 25, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Frank ZerbibC Prakash Gyawali
Jan 26, 2021·Health Technology Assessment : HTA·Janet A WilsonJames O'Hara

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