Comparison of ethinylestradiol and nonylphenol effects on reproduction of Chinese rare minnows (Gobiocypris rarus)

Ecotoxicology and Environmental Safety
Jinmiao ZhaZijian Wang

Abstract

Breeding pairs of rare minnows were exposed to 5, 10, 20 microg/L 4-nonylphenol (NP) or 4 ng/L 17alpha-ethinylestradiol (EE(2)) for 21 days. Among reproductive parameters investigated, fecundity, fertility, and laying interval were significantly affected by 4 ng/L EE(2), but were not affected at any exposure level of NP. These effects coincided with male feminization, ova-testis, increased plasma VTG in both males and females as well as the accumulation of eosinophilic material in kidneys and livers. Histopathologic evaluation revealed severe kidney lesions in both EE(2) and NP-exposed fish. The bioassay succeeded in demonstrating that EE(2) was several orders of magnitude more potent than the industrial chemical NP. The rare minnow was more sensitive to EE(2) than medaka, but comparable to zebrafish in terms of sensitivity. The results of the present investigation indicated that a short-term reproductive bioassay is feasible using the Chinese rare minnow as the test species.

References

Aug 1, 1994·Chemosphere·J TollsD T Sijm
Nov 9, 2001·Environmental Toxicology and Chemistry·H YokotaK Kobayashi
Aug 3, 2002·Environmental Toxicology and Chemistry·Masanori SekiKunio Kobayashi
Apr 12, 2003·Environmental Science & Technology·Karen L ThorpeCharles R Tyler
Oct 14, 2003·Environmental Toxicology and Chemistry·Ik Joon KangTsuneo Honjo
Oct 16, 2003·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·M SoléC Porte
Jun 8, 2004·Environmental Toxicology and Chemistry·Kevin V ThomasJohn E Thain
Jan 9, 2007·Aquatic Toxicology·Sonnich MeierAsbjørn Svardal

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Citations

Sep 24, 2014·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Ilaria BernabòElvira Brunelli
Jan 27, 2016·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Iman Shirdel, Mohammad Reza Kalbassi
Jan 23, 2016·Environmental Toxicology and Chemistry·Jiahua GuoAlistair B A Boxall
Jan 3, 2012·Environment International·E SychrováK Hilscherová
Jun 24, 2015·Ecotoxicology and Environmental Safety·A L OropesaM C Gil
Jul 3, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Jingjing WangZaizhao Wang
Nov 26, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Yuanxiang JinZhengwei Fu
Apr 11, 2012·Environmental Toxicology and Chemistry·Daniel J CaldwellJohn P Sumpter
Jan 10, 2012·Environmental Toxicology·Tracy M MontgomeryEthan D Clotfelter
Sep 8, 2010·Environmental Toxicology and Chemistry·Samiksha A Raut, Robert A Angus
May 7, 2015·Critical Reviews in Toxicology·Matthew D OverturfDouglas A Holdway
Apr 19, 2016·Environmental Toxicology and Chemistry·Thijs BoskerDeborah L MacLatchy
Dec 18, 2013·Environmental Science & Technology·Xiaowei JinZijian Wang

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