PMID: 9420671Jan 1, 1994Paper

Comparison of exercise, dipyridamole, and adenosine by use of technetium 99m sestamibi tomographic imaging

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
C D Santos-OcampoG Heller

Abstract

Pharmacologic stress has been shown in animal studies to induce high degrees of myocardial hyperemia. At these levels of myocardial blood flow, the myocardial uptake of technetium 99m sestamibi may plateau and may affect the diagnostic accuracy. This study compared the effects of myocardial hyperemia induced by exercise, dipyridamole, and adenosine on 99mTc sestamibi tomographic imaging in normal subjects and patients with ischemic coronary artery disease. Twenty subjects (group I, 10 normal subjects; group II, 10 patients with known coronary artery disease) underwent 99mTc sestamibi tomographic imaging after rest, exercise, dipyridamole infusion, and adenosine infusions on separate occasions. Total and background-corrected myocardial counts of the resulting images were calculated. Visual and computer-generated quantitative myocardial perfusion defect analysis was performed in subjects in group II. For subjects in both groups I and II, there were no significant differences in the background-corrected myocardial counts obtained with exercise, dipyridamole, and adenosine stress. There were no significant differences in the myocardial perfusion defects obtained after the three different modes of stress, including percentage defect...Continue Reading

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Citations

Aug 22, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Eliana ReyesS Richard Underwood
Nov 21, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Edoardo VernaSergio Ghiringhelli
Sep 2, 1998·The American Journal of Cardiology·A R ShehataG V Heller
May 9, 2000·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·I HŁjrisM Overgaard
May 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R TailleferM Jarry
May 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A S Iskandrian
Nov 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·G V Heller
Aug 26, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·M G LevineG V Heller
Sep 26, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Sujethra VasuAndrew E Arai
Oct 28, 2003·Circulation Journal : Official Journal of the Japanese Circulation Society·Masaki KawamuraShigeyuki Nishimura
May 15, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Farhood SaremiMichael E Siegel
Mar 17, 2001·Current Problems in Cardiology·D S BermanG Germano
May 20, 2014·JACC. Cardiovascular Interventions·Jamie LaylandColin Berry
Aug 13, 2011·JACC. Cardiovascular Imaging·Tust Techasith, Ricardo C Cury
Apr 17, 2001·Cardiology in Review·P Kailasnath, A J Sinusas
Jul 27, 2001·Nuclear Medicine Communications·B Hesse, A Kjaer
Mar 15, 2001·American Journal of Physiology. Heart and Circulatory Physiology·K WeiS Kaul

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