Comparison of field-of-view optimized and constrained undistorted single-shot diffusion-weighted imaging and conventional diffusion-weighted imaging of optic nerve and chiasma at 3T

Neuroradiology
Yuan TianLin Ma

Abstract

Single-shot echo-planar imaging is the conventional diffusion-weighted imaging (C-DWI) sequence for evaluating orbital disease. However, its utility is restricted in small organs like the chiasma and optic nerve. This study was conducted to investigate the utility of field-of-view optimized and constrained undistorted single-shot diffusion-weighted imaging (FOCUS-DWI) for evaluating the chiasma and optic nerve in acute optic neuritis, making comparisons with C-DWI. FOCUS-DWI and C-DWI were performed on 36 acute optic neuritis patients and 16 normal controls. Two readers assessed image quality using 5-point Likert scales. Differences in the visual assessments and apparent diffusion coefficient (ADC) values between C-DWI and FOCUS-DWI were evaluated. Inter-observer agreement in the qualitative data was assessed using Cohen's kappa coefficients. Inter- and intra-observer agreements in the ADC values were evaluated using intraclass correlation coefficients. FOCUS-DWI was superior to C-DWI in all aspects of the image evaluations. The Cohen's kappa coefficients for FOCUS-DWI were almost perfect (0.81-1) or substantial (0.61-0.80) for all the image quality categories. In the FOCUS-DWI images, the structural conspicuity of the chiasma ...Continue Reading

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Citations

May 3, 2019·AJNR. American Journal of Neuroradiology·L StunkelG P Van Stavern
Oct 12, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Salvatore MonacoFranco Alessandrini
Jul 17, 2021·AJNR. American Journal of Neuroradiology·L A DanyelE Siebert

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