Comparison of four types of intrauterine transfusion: effect on fetal hematocrit

Fetal Therapy
K J MoiseL E Cano

Abstract

The advent of cordocentesis has made it possible to treat fetuses affected by severe red cell alloimmunization by infusing red cells into umbilical vessels. In addition, serial hematocrits can be followed between transfusions. Twenty fetuses underwent a total of 118 intrauterine procedures. Four transfusion techniques were compared to assess the effect of each method on the stability of the fetal hematocrit between procedures. The change in hematocrit per day for direct intravascular transfusion was -1.06 +/- 0.68%, for intraperitoneal transfusion: +0.03 +/- 0.6%, for combined exchange intravascular and intraperitoneal transfusion: +0.02 +/- 0.3% and for combined direct intravascular and intraperitoneal technique: -0.01 +/- 0.4%. The greatest fall in hematocrit was noted with the use of the direct intravascular technique alone (p less than 0.001). The combined direct intravascular/intraperitoneal approach produces a stable hematocrit between procedures and offers the possibility of performing intrauterine transfusions at less frequent intervals.

Citations

Jul 1, 1996·Obstetrics and Gynecology·B Schumacher, K J Moise
May 5, 2001·Obstetrics and Gynecology·P W WhitecarK J Moise
Jan 1, 1997·Obstetrics and Gynecology·L A GoodrumK J Moise
Oct 11, 1992·American Journal of Obstetrics and Gynecology·K J MoiseD E Hesketh
Sep 11, 1992·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·D J SalaL Cordella-Simon
Jul 26, 2005·Seminars in Hematology·Kenneth J Moise
Oct 28, 1998·American Journal of Obstetrics and Gynecology·L HudonR J Carpenter
May 1, 1994·The Australian & New Zealand Journal of Obstetrics & Gynaecology·A J SampsonH Robinson
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Jodie M DoddInge L van Kamp
Jul 13, 2017·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J M DoddUNKNOWN MCA Doppler Study Group
Mar 28, 2019·Case Reports in Obstetrics and Gynecology·Roopali V Donepudi, Kenneth J Moise

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