PMID: 9187430Jan 1, 1997Paper

Comparison of gallium scan, computed tomography, and magnetic resonance in patients with mediastinal Hodgkin's disease

Annals of Oncology : Official Journal of the European Society for Medical Oncology
L DevizziG Bonadonna

Abstract

In patients with Hodgkin's disease, the use of gallium-67 scintigraphy (Ga-67) compared to conventional staging and restaging techniques is still controversial. In particular, in a combined modality treatment with chemotherapy and radiotherapy given in sequence, its role in detecting active disease after chemotherapy may be useful in planning the subsequent radiotherapeutic strategy. From March 1990 to September 1994, 125 patients with previously untreated histologically proven Hodgkin's disease were enrolled in two different prospective trials according to clinical stage. Staging procedures included Ga-67, chest-abdominal computed tomography (CT), and/or magnetic resonance (MR). All three tests were performed in 53 patients at staging and in 47 at restaging. Results of Ga-67 at staging were compared to conventional procedures or pathological findings. Results of Ga-67, CT scan, and MR at restaging were compared to disease outcome during the follow-up. Finally a cost/benefit ratio for each test was determined. At staging, Ga-67 showed lower sensitivity than CT and MR (90 vs. 96 and 100%, respectively) because of the number of false-negative images. Nevertheless, by using both CT and Ga-67 scan, the sensitivity is equal to that ...Continue Reading

Citations

Mar 20, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Einat Even-Sapir, Ora Israel
Jun 23, 2000·Critical Reviews in Oncology/hematology·H EghbaliP Richaud
Dec 20, 2005·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Alain RahmouniEmmanuel Itti
Mar 15, 2006·Mayo Clinic Proceedings·Stephen M Ansell, James O Armitage
Dec 7, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Hilke VorwerkElisabeth Weiss
Aug 22, 2007·Blood·Pamela SeamBruce D Cheson
Aug 5, 2017·Topics in Magnetic Resonance Imaging : TMRI·Brett W CarterMarcelo F Benveniste

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