Comparison of gastrointestinal morbidity after Norwood and hybrid palliation for complex heart defects

Pediatric Cardiology
Scott L WeissEric L Wald

Abstract

This study aimed to compare the incidence of gastrointestinal complications among infants with single-ventricle heart defects after three first-stage palliation strategies: Norwood-modified Blalock-Taussig shunt (mBTS), Norwood right ventricle-to-pulmonary artery conduit (Sano), and hybrid procedures. A retrospective chart review was performed in a pediatric cardiac intensive care unit at a tertiary care medical center. The subjects were 32 neonates who had undergone single-ventricle palliation including 13 Norwood-mBTS, 11 Sano, and 8 hybrid procedures. The measurements included baseline as well as pre- and postoperative patient characteristics. The primary outcome was postoperative intraabdominal complications, and the secondary outcomes were feeding intolerance and necrotizing enterocolitis (NEC). Intraabdominal complications occurred for 34%, feeding intolerance for 13%, and NEC for 13% of the patients. The hybrid patients had a higher incidence of intraabdominal complications (75%) than the Norwood-mBTS (31%) or Sano (9%) patients (P = 0.01). The relative risk for intraabdominal complications in the hybrid group was 3.6 (95% confidence interval [CI], 1.5-8.7). In the multivariate analysis, the hybrid procedure remained an ...Continue Reading

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Citations

Apr 2, 2014·The Journal of Thoracic and Cardiovascular Surgery·Alexander A BresciaCharles B Huddleston
Jan 1, 2013·The Annals of Thoracic Surgery·Ryan R DaviesChristian Pizarro
Apr 3, 2016·Congenital Heart Disease·Elizabeth A MitchellClifford L Cua

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