PMID: 11331233May 2, 2001Paper

Comparison of genomic DNA sequences: solved and unsolved problems

Bioinformatics
W Miller

Abstract

The DNA sequences of entire genomes are being determined at a rapid rate. Whereas initial genome sequencing efforts were for organisms chosen to be widely spaced in the tree of life, there is a growing emphasis on projects to sequence a species that is sufficiently similar to an already-sequenced species to allow direct comparison of those two DNA sequences. This and other changes in genome sequencing strategies have created a strong need for new methods to compare genomic sequences. We sketch the current state of software for comparing genomic DNA sequences and outline research directions that we believe are likely to result in important advances in practice.

Citations

Feb 23, 2008·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Thomas Faraut
Feb 19, 2002·Current Opinion in Biotechnology·N Goodman
Dec 7, 2002·The International Journal of Biochemistry & Cell Biology·Ling-Hui ZhangChih-Chuan Liang
Sep 30, 2010·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Giltae SongWebb Miller
Dec 14, 2011·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Hugo Devillers, Sophie Schbath
Sep 9, 2011·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Hugo DevillersMeriem El Karoui
Apr 12, 2006·Bioinformatics·Radek Szklarczyk, Jaap Heringa
Oct 5, 2002·Nucleic Acids Research·Catherine MathéPierre Rouzé
Dec 5, 2003·Nucleic Acids Research·Jonathan E Moore, James A Lake
Jun 25, 2004·Nucleic Acids Research·Michael BrudnoBurkhard Morgenstern
Jun 25, 2004·Nucleic Acids Research·Burkhard Morgenstern
Jan 11, 2005·Nucleic Acids Research·Liang Ye, Xiaoqiu Huang
Jun 28, 2005·Nucleic Acids Research·Dirk PöhlerBurkhard Morgenstern
Apr 3, 2004·Genome Research·Von Bing Yap, Lior Pachter
Mar 26, 2003·Genome Research·Michael BrudnoSerafim Batzoglou
Oct 7, 2003·Annual Review of Genomics and Human Genetics·Jennifer L Ashurst, John E Collins
Oct 16, 2004·Annual Review of Genomics and Human Genetics·Webb MillerRoss C Hardison
May 11, 2007·Annual Review of Genomics and Human Genetics·Mathieu Blanchette
May 4, 2010·BMC Bioinformatics·Ryuichiro Nakato, Osamu Gotoh
Dec 25, 2003·BMC Bioinformatics·Michael BrudnoBurkhard Morgenstern
Sep 11, 2004·BMC Bioinformatics·Martin SchmollingerBurkhard Morgenstern
Jan 23, 2004·BMC Bioinformatics·Daniel A PollardMichael B Eisen
Oct 26, 2005·BMC Bioinformatics·Alexander ChurbanovHesham Ali
Oct 30, 2007·BMC Bioinformatics·Adrienne X WangMartin Tompa
Jul 30, 2011·BMC Evolutionary Biology·Giltae SongWebb Miller
Dec 9, 2003·Genome Biology·Inna Dubchak, Kelly Frazer
May 30, 2009·PLoS Computational Biology·Robert K BradleyLior Pachter
Aug 28, 2009·The Journal of Molecular Diagnostics : JMD·Ayman El-SeedyVéronique Ladeveze
Oct 31, 2009·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Amol Prakash, Martin Tompa
Oct 19, 2006·IEEE/ACM Transactions on Computational Biology and Bioinformatics·Nadia PisantiMarie-France Sagot
Jun 9, 2005·IEEE Transactions on Neural Networks·Rui Xu, Donald Wunsch
Jun 28, 2005·Computational Biology and Chemistry·Jeong-Hyeon ChoiSun Kim
Apr 18, 2015·BMC Bioinformatics·Raluca UricaruEric Rivals
Dec 12, 2002·Journal of Biomedical Informatics·Liping WeiJohn Park
Apr 3, 2003·Nature Reviews. Genetics·Abel Ureta-VidalEwan Birney
Jul 8, 2005·Microbiology·Dawn FieldGareth A Wilson
Jan 17, 2003·Genome Research·Olivier CouronneInna Dubchak
Jan 17, 2003·Genome Research·Nick BrayLior Pachter
Jan 17, 2003·Genome Research·Scott SchwartzWebb Miller
Jan 17, 2003·Genome Research·Genís ParraRoderic Guigó

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.