Comparison of hemoglobin A1c and fasting glucose criteria to diagnose diabetes among people with metabolic syndrome and fasting glucose above 100 mg/dL (5.5 mmol/L)

The Journal of Clinical Hypertension
Evangelos N LiberopoulosMoses S Elisaf

Abstract

The aim of this study was to compare hemoglobin A(1c) (HbA(1c)) and fasting glucose for the diagnosis of diabetes among people with metabolic syndrome and fasting glucose >100 mg/dL (5.5 mmol/L). Consecutive individuals (N=142) with metabolic syndrome and fasting glucose >100 mg/dL (5.5 mmol/L) but without a self-reported history of diabetes who visited the outpatient lipid and obesity clinic of the University Hospital of Ioannina, Greece from January through September 2009 were included. HbA(1c)> or =6.5% and fasting glucose > or =126 mg/dL (7 mmol/L) were used separately to define diabetes. Overall, 29.5% of patients had both HbA(1c)> or =6.5% and fasting glucose > or =126 mg/dL (7 mmol/L), 25.3% had HbA(1c)> or =6.5% but fasting glucose <126 mg/dL (7 mmol/L), and 9.1% had HbA(1c) <6.5% but fasting glucose > or =126 mg/dL (7 mmol/L). A greater proportion of patients reached a diagnosis of diabetes based on the HbA(1c) criterion (n=78, 54.9%) compared with the fasting glucose criterion (n=55, 38.7%, P=.000). A large proportion of patients (44.8%) with impaired fasting glucose (fasting glucose 100-125 mg/dL; 5.6-6.9 mmol/L) would be classified as diabetics using the HbA(1c) criterion. Implication of the HbA(1c) criterion may in...Continue Reading

References

Aug 21, 2002·Annals of Internal Medicine·R Graham BarrDaniel E Singer
May 27, 2004·Diabetes Care·Tara M WallaceDavid R Matthews
Feb 7, 2009·Diabetes Care·Elizabeth SelvinFrederick L Brancati
Mar 21, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity·Randie R Little, David B Sacks
Jun 9, 2009·Diabetes Care·UNKNOWN International Expert Committee
Jan 29, 2010·Diabetes Care·UNKNOWN American Diabetes Association

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Citations

Oct 4, 2011·Journal of Pharmacy & Bioallied Sciences·Arunpreet Singh Kahlon, Rambha Pathak
Feb 25, 2014·The American Journal of Medicine·Preethi Srikanthan, Arun S Karlamangla
May 3, 2013·European Journal of Clinical Investigation·Shuang YanQiang Li
Dec 24, 2019·Hypertension·Christianne L RoumieUNKNOWN SPRINT Research Group
Mar 12, 2021·Journal of Cellular and Molecular Medicine·Shuai YuanDao Wen Wang

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