Comparison of hemostatic sealants on ovarian reserve during laparoscopic ovarian cystectomy

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Jun Hyeok KangWoo Young Kim

Abstract

To determine whether different methods of hemostasis and pathologic subtypes would lead to significant differences regarding ovarian reserve after laparoscopic ovarian cystectomy. Data were prospectively collected from 129 patients who underwent laparoscopic ovarian cystectomy with either a hemostatic sealant (FloSeal or TachoSil) or bipolar coagulation to achieve hemostasis. Serum anti-Müllerian hormone (AMH) levels as measured by enzyme immunoassay. Measurements were made preoperatively and at 3 months postsurgery in each group [bipolar coagulator group (n=43), FloSeal group (n=46), and TachoSil group (n=40)]. Age, BMI, parity, sociodemographic variables, and preoperative AMH levels were similar between the three groups of patients. At 3 months post-surgery, the AMH decline rate was significantly greater in the bipolar coagulation group compared with the two hemostatic sealant groups (41.2% [IQR, 16.7-52.4] vs. 15.4% [IQR, 5.2-41.9], respectively; P=0.003). However, the AMH decline rates of the two hemostatic sealant groups (FloSeal and TachoSil) were not significantly different (15.4% [IQR, 7.8-44.6] vs. 15.9% [IQR, 0.7-41.1], P=0.962). Also, subgroup analysis according to ovarian cyst type revealed no significant difference...Continue Reading

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Citations

Apr 10, 2016·American Journal of Obstetrics and Gynecology·Ahmed A MohamedSaad A Amer
Jan 11, 2020·Obstetrics and Gynecology·Anne M Stachowicz, James L Whiteside
Apr 24, 2020·Current Opinion in Obstetrics & Gynecology·Rachel M CulliferTerri Huynh
Jun 20, 2020·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Rodrigo Manieri Rocha, Ionara Diniz Evangelista Santos Barcelos
Oct 6, 2017·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Paula DeckersEdmund Chada Baracat
Dec 23, 2017·The Journal of Obstetrics and Gynaecology Research·Chahien ChoiSan Hui Lee
Apr 21, 2021·Scientific Reports·Soo Jin ParkUNKNOWN PRAHA Study Group

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