Comparison of Hilar Clamping Techniques in Partial Nephrectomy: Is Artery Only Clamping Beneficial?

Indian Journal of Surgical Oncology
Kil-Hun Song, Wol-Song Jang

Abstract

Hilar clamping is widely adopted in open partial nephrectomy, which is a treatment option for small renal cancer to reduce blood loss and improve surgical exposure, but whether to clamp either only artery or both artery and vein remains controversial. The purpose of this study is to determine whether artery only (AO) clamping is more beneficial than en bloc clamping by comparing perioperative variables in patients who underwent partial nephrectomy with either AO clamping or en bloc clamping. Eighty-eight patients with T1 renal tumor who underwent open partial nephrectomy with either AO or en bloc clamping between 2015 and 2018 at our institution were enrolled. They were randomly divided into two groups: AO group (n = 43) and artery and vein (AV) group (n = 45). Renal function was evaluated by serum creatinine (SCr) and differential renal function as determined by mercaptoacetyltriglycine renogram. AO clamping was associated with less total renal functional decrease until postoperative 7th day (P < 0.05). After postoperative 15th day, however, there was no significant difference in total renal functional impairment between AO and AV groups. There was also no significant difference in differential renal function change. Furthermo...Continue Reading

References

Feb 11, 2004·Cancer·Alessandro VolpeMichael A S Jewett
Aug 24, 2007·The New England Journal of Medicine·J Gary Abuelo
Aug 2, 2008·Current Opinion in Urology·Andre BergerInderbir S Gill
Sep 10, 2010·European Urology·R Houston ThompsonSteven C Campbell
Feb 1, 2015·The Journal of Urology·Maria C MirSteven C Campbell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.