Comparison of hydraulic and hemolytic properties of different impeller designs of an implantable rotary blood pump by computational fluid dynamics

Artificial Organs
Arash ArvandHelmut Reul

Abstract

A mixed-flow blood pump for long-term applications has been developed at the Helmholtz-Institute in Aachen, Germany. Central features of this implantable pump are a centrally integrated motor, a blood-immersed mechanical bearing, magnetic coupling of the impeller, and a shrouded impeller, which allows a relatively wide clearance. The aim of the study was a numerical analysis of hydraulic and hemolytic properties of different impeller design configurations. In vitro testing and numerical simulation techniques (computational fluid dynamics [CFD]) were applied to achieve a comprehensive overview. Pressure-flow charts were experimentally measured in a mock loop in order to validate the CFD data. In vitro hemolysis tests were performed at the main operating point of each impeller design. General flow patterns, pressure-flow charts, secondary flow rates, torque, and axial forces on the impeller were calculated by means of CFD. Furthermore, based on streak line techniques, shear stress (stress loading), exposure times, and volume percentage with critical stress loading have been determined. Comparison of CFD data with pressure head measurements showed excel-lent agreement. Also, impressive trend conformity was observed between in-vitr...Continue Reading

References

Jun 5, 2003·Artificial Organs·Reinhard PaulHelmut Reul

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Citations

Feb 24, 2005·Artificial Organs·Paul S Malchesky
Sep 25, 2009·Artificial Organs·Fangjun ShuJames F Antaki
Mar 19, 2015·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Kohei IshiiYusuke Abe
Nov 16, 2010·Medical Engineering & Physics·Katharine H FraserZhongjun J Wu
Dec 13, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Stijn VandenberghePascal R Verdonck
Nov 19, 2015·Cardiovascular Engineering and Technology·Fangjun ShuJames F Antaki
Jul 1, 2021·Biomechanics and Modeling in Mechanobiology·Mohamad Sadeq KarimiAhmad Nourbakhsh

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