Comparison of Image Quality and Diagnostic Performance of Cone-Beam CT during Drug-Eluting Embolic Transarterial Chemoembolization and Multidetector CT in the Detection of Hepatocellular Carcinoma

Journal of Vascular and Interventional Radiology : JVIR
Pierleone LucatelliMario Bezzi

Abstract

To compare image quality and diagnostic performance of cone-beam computed tomography (CT) and multidetector CT in the detection of hypervascular hepatocellular carcinoma (HCC) in patients with cirrhosis undergoing transarterial chemoembolization with drug-eluting embolic agents. Fifty-five consecutive patients referred for chemoembolization of hypervascular HCC were prospectively enrolled. Imaging included preprocedural multidetector CT within 1 month before planned treatment, intraprocedural cone-beam CT, and 1-month follow-up multidetector CT. Analysis of image quality was performed with calculations of lesion-to-liver contrast-to-noise ratio (LLCNR) and lesion-to-liver signal-to-noise-ratio (LLSNR). One-month follow-up multidetector CT was considered the reference standard for the detection of HCC nodules. Median LLCNR values were 3.94 (95% confidence interval [CI], 3.06-5.05) for preprocedural multidetector CT and 6.90 (95% CI, 5.17-7.77) for intraprocedural cone-beam CT (P < .0001). Median LLSNR values were 11.53 (95% CI, 9.51-12.44) for preprocedural multidetector CT and 9.36 (95% CI, 8.12-10.39) for intraprocedural cone-beam CT (P < .0104). Preprocedural multidetector CT detected 115 hypervascular nodules with typical HC...Continue Reading

Citations

Apr 14, 2018·Cardiovascular and Interventional Radiology·Pierleone LucatelliMario Bezzi
May 4, 2018·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Tanja ZitzelsbergerUlrich Grosse
Apr 27, 2021·Journal of Vascular and Interventional Radiology : JVIR·Mohamed ElboraeyBeau B Toskich
Sep 25, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Frank H MillerRobert J Lewandowski

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