PMID: 2511230Nov 1, 1989Paper

Comparison of immunodiffusion and enzyme linked immunosorbent assay for antibodies to four Aspergillus species

Journal of Clinical Pathology
J H FroudistR McAleer

Abstract

Antigenic extracts were prepared from Aspergillus fumigatus, A niger, A flavus and A terreus for use in enzyme linked immunosorbent assay (ELISA) and immunodiffusion (ID) tests for Aspergillus antibodies to determine whether the use of antigenic extracts from species other than A fumigatus increased the sensitivity of the ELISA. ELISA titres correlated well with positive ID tests. Patient titres by ELISA were significantly higher than control titres for all species. Patient titres to A niger were also significantly higher than titres to the other species. Total number of ID bands to A fumigatus correlated significantly with anti-A fumigatus ELISA titres. It is concluded that the use of antigenic extracts from species other than A fumigatus improves the sensitivity of the ELISA.

References

Apr 1, 1976·Journal of Biological Standardization·C M Philpot, D W Mackenzie
Jan 1, 1984·International Archives of Allergy and Applied Immunology·H Schønheyder, P Andersen
Jul 1, 1980·The Journal of Infectious Diseases·J W GoldD Armstrong
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Citations

Sep 1, 1995·Mycopathologia·T K Graczyk, J F Cockrem
Jan 1, 1990·Virchows Archiv. A, Pathological Anatomy and Histopathology·J N CoxN Pochon
Jun 1, 1991·Journal of Clinical Pathology·A P BoonD H Adams
May 10, 2008·Scandinavian Journal of Rheumatology·T KotaniT Hanafusa

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Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Aspergillosis

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

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