Comparison of in vitro fertilisation success in patients with polycystic ovary syndrome and tubal factor

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Ensieh Shahrokh Tehrani NejadNadia Jahangiri

Abstract

This study is designed to compare the results of in vitro fertilisation (IVF) in polycystic ovary syndrome (PCOS) and tubal factor disorders. This was a cohort study performed in Royan Institute from 2007 to 2009. For this evaluation, 183 patients with PCOS and 183 patients with tubal factor (control group), whose ages ranged from 22 to 35 years underwent the long protocol of pituitary suppression and were included in the study. In a defined time cycle, the number of ampoules used was higher for the control group (24.6 ± 0.9 versus 33.4 ± 0.9; p<0.0001). The PCOS group produced more oocytes (9.6 ± 0.5 versus 6.4 ± 0.3; p ≤ 0.0001) and embryos (3.7 ± 0.2 versus 2.7 ± 0.1; p=0.001). There were no significant differences in cancellation rate, the occurrence of ovarian hyperstimulation syndrome (OHSS) and cycles that resulted in lacked efficient follicle in the PCOS group and control group. Comparisons for biochemical pregnancy, implantation, clinical pregnancy and ongoing pregnancy rates showed no statistical difference. No significant differences were detected in miscarriage rates and complications. The outcome of IVF in patients with PCOS and in patients with tubal infertility is similar.

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Citations

Aug 5, 2011·Human Reproduction·Vivian RittenbergTarek El-Toukhy
Aug 19, 2011·Reproductive Biology and Endocrinology : RB&E·Norbert GleicherDavid H Barad
Apr 1, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Liu LiuSongying Zhang
Jul 23, 2015·Reproduction : the Official Journal of the Society for the Study of Fertility·Fang YangJian-Zhi Yang
Jan 24, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Mahnaz Bahri KhomamiLisa J Moran
Oct 31, 2012·Current Opinion in Endocrinology, Diabetes, and Obesity·Rebecca S Usadi, Richard S Legro
Sep 28, 2017·Journal of Assisted Reproduction and Genetics·José BellverUNKNOWN Group of interest in Reproductive Endocrinology (GIER) of the Spanish Fertility Society (SEF)

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