Comparison of Intralesional Measles, Mumps, Rubella Vaccine and Needling in the Treatment of Recurrent Warts

Journal of Cutaneous and Aesthetic Surgery
Surabhi R Kolte, Vidyadhar R Sardesai

Abstract

Warts constitute 21% of all the cases in a dermatology clinic. Their causative agent is the human papillomavirus (HPV). Most of the cutaneous warts are cosmetically disfiguring and their treatment requires patience by both the practitioner and the patients. This study aimed to compare the efficacy of intralesional measles, mumps, rubella (MMR) vaccine and needling in the treatment of recurrent warts. This was a prospective, comparative, and interventional study. This hospital-based study was conducted in a tertiary health-care center from September 2017 to August 2019. Overall 40 patients of recurrent warts were included in the study. Fisher test, Student t test, and chi-square test were used for statistical analysis. Improvement was noted in patients belonging to both the groups. However, after applying chi-square test, it was found that results were statistically significant in the needling group only. When both the groups were compared using chi-square test, needling showed statistically significant results after 4 and 6 weeks. Needling was observed to be a better treatment modality as compared to intralesional MMR vaccine at the end of 4 and 6 weeks. More number of sessions were required in the intralesional MMR vaccine gro...Continue Reading

References

Feb 1, 1969·Journal of the American Podiatry Association·G W Falknor
Dec 2, 2004·Dermatologic Therapy·Allison Rivera, Stephen K Tyring
Jul 21, 2006·The Cochrane Database of Systematic Reviews·S Gibbs, I Harvey
Jul 30, 2014·International Journal of Dermatology·Ahmad NofalHager Nofal
Apr 19, 2016·Indian Journal of Dermatology, Venereology and Leprology·Poonam SainiSharad Mehta
Dec 16, 2016·Case Reports in Urology·Peri Eriad YunirRainy Umbas

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