Comparison of Long-Term Outcomes of Femtosecond Laser-Assisted Keratoplasty with Conventional Keratoplasty

Cornea
Moritz C DanielT Reinhard

Abstract

Astigmatism is a significant problem in penetrating keratoplasty. Lower astigmatism and better visual outcomes had been expected from laser-assisted penetrating keratoplasty, that is, from the top-hat, mushroom, or zig-zag cutting profiles. We report the long-term outcomes of 141 femtosecond laser-assisted penetrating keratoplasties retrospectively. We compare these outcomes with those of penetrating keratoplasty using the guided trephine system (GTS). In all, 141 femtosecond laser-assisted penetrating keratoplasties had been performed in 119 patients. The results were compared with those of conventional keratoplasty (n = 1254; visual and refractive outcomes, graft rejections, and graft failure). Follow-up averaged 33 months. In eyes with keratoconus, the time to achieve a visual acuity of 10/20 (Snellen) was shorter in the mushroom than in the GTS group. However, there was no relevant long-term difference. Graft astigmatism was higher in the laser groups [keratometric astigmatism at the end of follow-up: -4.5 ± 4 (GTS), -5.8 ± 3.3 (top-hat), -5.9 ± 3.2 D (mushroom); P < 0.01]. In eyes with keratoconus, rates of graft rejection were highest in the mushroom group (55%). In the other groups, top-hat keratoplasty resulted in lower...Continue Reading

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Citations

Mar 7, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gábor TóthNóra Szentmáry
Dec 23, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·F SchaubC Cursiefen
Jun 20, 2019·Vestnik oftalmologii·G A OsipyanKh Khraystin
Jan 23, 2020·Current Eye Research·Karl Thomas BodenAnnekatrin Rickmann
Jul 30, 2017·Ophthalmology and Therapy·Konstantinos D AndreanosGeorge D Kymionis
Mar 29, 2020·The British Journal of Ophthalmology·Pranita SahayRasik B Vajpayee
Feb 2, 2021·Survey of Ophthalmology·Rashmi DeshmukhRasik B Vajpayee

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