Comparison of Methods for Xenomonitoring in Vectors of Lymphatic Filariasis in Northeastern Tanzania

The American Journal of Tropical Medicine and Hygiene
Seth R IrishMary M Cameron

Abstract

Monitoring Wuchereria bancrofti infection in mosquitoes (xenomonitoring) can play an important role in determining when lymphatic filariasis has been eliminated, or in focusing control efforts. As mosquito infection rates can be low, a method for collecting large numbers of mosquitoes is necessary. Gravid traps collected large numbers of Culex quinquefasciatus in Tanzania, and a collection method that targets mosquitoes that have already fed could result in increased sensitivity in detecting W. bancrofti-infected mosquitoes. The aim of this experiment was to test this hypothesis by comparing U.S. Centers for Disease Control and Prevention (CDC) light traps with CDC gravid traps in northeastern Tanzania, where Cx. quinquefasciatus is a vector of lymphatic filariasis. After an initial study where small numbers of mosquitoes were collected, a second study collected 16,316 Cx. quinquefasciatus in 60 gravid trap-nights and 240 light trap-nights. Mosquitoes were pooled and tested for presence of W. bancrofti DNA. Light and gravid traps collected similar numbers of mosquitoes per trap-night, but the physiological status of the mosquitoes was different. The estimated infection rate in mosquitoes collected in light traps was considerabl...Continue Reading

References

Jan 1, 1971·Transactions of the Royal Society of Tropical Medicine and Hygiene·G B White
Sep 14, 1999·Medical and Veterinary Entomology·M J BockarieM P Alpers
Oct 22, 2004·Emerging Infectious Diseases·William ReisenJohn Edman
Oct 6, 2006·Journal of the American Mosquito Control Association·Gary LukacikDennis J White
Feb 12, 2008·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Gregory M Williams, Jack B Gingrich
Oct 27, 2009·Journal of the American Mosquito Control Association·Bruce A HarrisonGail R Hansen
Aug 18, 2012·Journal of Medical Entomology·Jeronimo AlencarElias Seixas Lorosa
Dec 12, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Seth R IrishMary M Cameron

❮ Previous
Next ❯

Citations

Oct 7, 2017·PLoS Neglected Tropical Diseases·Yahya A DeruaLeonard E G Mboera
Dec 29, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Mary M Cameron, Anita Ramesh
Apr 28, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph Pryce, Lisa J Reimer

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR in Malaria

CRISPR-Cas system enables the editing of genes to create or correct mutations. This technology is being investigated to combat malaria by targeting specific stretches of vector DNA and editing the genome at precise locations. Here is the latest research.