Comparison of microRNA Profiles between Bovine Mammary Glands Infected with Staphylococcus aureus and Escherichia coli

International Journal of Biological Sciences
Zhuo-Ma LuorengLin-Sen Zan

Abstract

MicroRNAs (miRNAs) play crucial roles in regulating innate and adaptive immunity in humans and animals. Infection with E. coli or S. aureus can cause inflammation of the mammary glands, which results in significant economic losses in dairy cattle. However, the regulatory mechanisms of miRNAs in response to E. coli or S. aureus infection in bovine mammary glands have not been thoroughly explored. To discover the differential expression of miRNA in bovine mammary gland challenged with E. coli or S. aureus, we performed miRNA sequencing on tissue samples. A total of 1838 miRNAs were identified, including 580 known-miRNAs (included in the miRbase database) and 1258 predicted novel miRNAs. The miRNA expression patterns indicated that, compared with control samples, 279 miRNAs and 305 miRNAs were differentially expressed miRNAs (DIE-miRNA) in S. aureus and E. coli infected tissues, respectively. Moreover, the results of comparison the DIE-miRNAs between the E. coli and S. aureus infected groups showed that 197 DIE-miRNAs are identical, 108 DIE-miRNAs are specific to the E. coli group, and 82 DIE-miRNAs are specific to the S. aureus group. Many DIE-miRNAs, such as bta-miR-144, bta-miR-451 and bta-miR-7863, might be the useful biomarke...Continue Reading

Citations

Nov 14, 2019·Journal of Veterinary Internal Medicine·Lisbeth R JessenSusanna Cirera
Mar 4, 2020·Mikrochimica Acta·Adrián Sánchez-VisedoMaría Teresa Fernández-Argüelles
Dec 26, 2018·Journal of Dairy Science·Julie Côté-Gravel, François Malouin
Sep 20, 2020·FEMS Microbiology Ecology·Vanessa SilvaPatrícia Poeta
Jan 5, 2021·Frontiers in Veterinary Science·Silvia MirettiMario Baratta
Nov 10, 2020·Research in Veterinary Science·Yu-Chang LaiNaoki Miura
Oct 30, 2020·International Journal of Molecular Sciences·Ankita SharmaNiel A Karrow
May 1, 2019·Comprehensive Reviews in Food Science and Food Safety·Abderrahim Benmoussa, Patrick Provost
Apr 4, 2021·International Journal of Molecular Sciences·Duy N DoEveline M Ibeagha-Awemu
Jul 28, 2021·In Vitro Cellular & Developmental Biology. Animal·Haotian XuJianfa Wang
Aug 11, 2018·Journal of Agricultural and Food Chemistry·Huimin ZhangZhangping Yang
Sep 22, 2021·The Journal of Immunology : Official Journal of the American Association of Immunologists·P Thamarasseri DhanagovindSanjita Banerjee
Oct 13, 2021·Journal, Genetic Engineering & Biotechnology·Farmanullah FarmanullahZhang Shujun

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Methods Mentioned

BETA
RNA-seq
PCR
biopsies
RNAseq

Software Mentioned

IDEG6
GOseq R
cBot Cluster Generation System
miRnada
Bowtie
miRDeep2
Randfold
RNAhybrid

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