Comparison of morphine and ropivacaine following knee arthroscopy

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association
F FranceschiV Denaro

Abstract

The purpose of this study was to compare the effectiveness of ropivacaine, a new local amidic anesthetic, compared with morphine as an intra-articular drug in controlling pain in patients after arthroscopic knee surgery. Randomized trial. We enrolled 90 patients scheduled to undergo elective knee arthroscopy. Patients were homogenous regarding demographic data and ASA physical status. Procedures included were diagnostic arthroscopies, lateral and medial meniscectomies, meniscal repair, and removal of loose bodies. All cases were treated by the same surgeon, under general anesthesia, using the same procedure. Patients were randomly divided into 3 groups. The first group received ropivacaine 75 mg in 20 mL of saline solution, the second group received 2 mg morphine in 20 mL of saline solution, and the third group received 20 mL of saline solution. No other oral or injectable analgesic administration was allowed. A blind observer assessed the patients' postoperative pain using a 10-cm visual analogue scale (VAS), ranging from no pain (0) to unbearable pain (10). Scores were taken at 0, 1, 4, 6, 12, and 24 hours after drug injection. VAS scores were analyzed using analysis of variance; significance was set at P <.005. None of the p...Continue Reading

Associated Clinical Trials

Citations

Mar 10, 2005·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Emmanuel MarretFrancis Bonnet
Feb 24, 2006·The American Journal of Sports Medicine·G William WoodsCynthia T Calder
Nov 23, 2017·Journal of Orthopaedic Surgery and Research·Xiaojun ChenYong Zhu
May 4, 2016·The Cochrane Database of Systematic Reviews·Zui ZouXue Y Shi
Jan 1, 2008·The Open Orthopaedics Journal·G I DrososD-A Verettas
Jun 8, 2015·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Yang ZhouGuang-Hua Lei
May 1, 2021·International Journal of Environmental Research and Public Health·Shao-Chun WuYan-Yuen Poon
Apr 29, 2009·Veterinary Anaesthesia and Analgesia·Luiz César Pereira SantosMere Erika Saito

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