Comparison of mortality rates and progression of left ventricular dysfunction in patients with idiopathic dilated cardiomyopathy and dilated versus nondilated right ventricular cavities

The American Journal of Cardiology
J P SunW J Stewart

Abstract

This study assesses the influence of right ventricular (RV) dilation on the progression of left ventricular (LV) dysfunction and survival in patients with idiopathic dilated cardiomyopathy (IDC). Using transthoracic echocardiography, we studied 100 patients with IDC aged 20 to 80 years (mean 55 +/- 14); 67% were men. In the apical 4-chamber view, diastolic LV and RV chamber area measurements classified patients into 2 groups: group RV enlargement+ (RV area/LV area > 0.5) included 54 patients; group RV enlargement- (no RV enlargement) had RV area/LV area < or = 0.5. Echocardiographic studies were repeated in all patients after a mean of 33 +/- 16 months. At the time of the initial study, the 2 groups did not differ in age, gender, incidence of atrial fibrillation and diabetes, left ventricular mass, and LV ejection fraction, but the RV enlargement+ group had more severe tricuspid regurgitation and less LV enlargement. After 47 +/- 22 months (range 12 to 96), patients in group RV enlargement+ had lower LV ejection fraction (29% vs 34%, p = 0.006) than patients with initial RV enlargement-. At clinical follow-up, mortality was higher (43%) in patients with initial RV enlargement+ than the RV enlargement- patients (15%), p = 0.002....Continue Reading

References

Sep 1, 1978·Current Problems in Cardiology·J P SegalW P Harvey
Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Jul 1, 1984·The American Journal of Cardiology·D V UnverferthC V Leier
Oct 21, 1982·The New England Journal of Medicine·R A Johnson, I Palacios
Oct 28, 1982·The New England Journal of Medicine·R A Johnson, I Palacios
Mar 1, 1981·The American Journal of Cardiology·V FusterR L Frye

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Citations

Oct 14, 2014·Biomarkers in Medicine·Hythem Nawaytou, Harold S Bernstein
Jul 8, 2008·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Amr YoussefNael F Osman
Feb 24, 2010·Circulation. Heart Failure·David VerhaertW H Wilson Tang
Sep 22, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·André Y DenaultJean-Claude Tardif
May 23, 2006·AJR. American Journal of Roentgenology·Halil DoğanAlbert de Roos
Jul 29, 2011·Heart Failure Reviews·Maya Guglin, Sameer Verma
May 29, 2012·The Annals of Thoracic Surgery·Joern KarhausenG Burkhard Mackensen
Nov 23, 2011·Radiología·A Capelastegui AlberT Salinas Yeregui
Jun 15, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Laura FusiniMauro Pepi
Jun 28, 2011·Journal of Cardiac Failure·Michael EssGerhard Poelzl
Jul 1, 2009·Heart Failure Clinics·Frank Grothues, Ruediger Braun-Dullaeus
Aug 3, 2011·European Journal of Clinical Investigation·Gerhard PoelzlHanno Ulmer
Apr 2, 2016·Archives of Cardiovascular Diseases·Pascal de Groote
Aug 12, 2006·International Journal of Cardiology·Gillian A WhalleyRobert N Doughty
Jun 6, 2006·International Journal of Cardiology·Gloria TamboriniFabrizio Veglia
Jun 6, 2006·Journal of Cardiothoracic and Vascular Anesthesia·Arnaud RobitailleRaymond Martineau
Dec 6, 2005·Journal of Cardiothoracic and Vascular Anesthesia·Maïté CarricartJean Buithieu
Dec 17, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Daniel S KnightJoseph Davar
Apr 30, 2016·Pediatric Cardiology·Francois RoubertiePierre Bordachar
Jul 16, 2005·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Nancy McLaughlinAndré Denault
Jul 28, 2016·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·J M Gentile-Solomon, J A Abbott
Mar 3, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Gloria TamboriniMauro Pepi
Jan 24, 2015·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Enrico VizzardiMarco Metra
May 18, 2018·Circulation. Arrhythmia and Electrophysiology·Niyada NaksukChristopher J McLeod
Apr 2, 2008·Circulation·Maria M GonzalezJose A Ramires
Oct 25, 2006·Circulation·Norbert F VoelkelUNKNOWN National Heart, Lung, and Blood Institute Working Group on Cellular and Molecular Mechanisms of Right Heart Failure
Jul 27, 2018·Journal of Cardiovascular Medicine·Valentina MercurioSavina Nodari
Feb 15, 2008·Critical Care Medicine·Helene GlassbergVictor A Ferrari
Mar 23, 2002·International Anesthesiology Clinics·Andrew MaslowScott Mackinnon
Oct 7, 2010·Nature Reviews. Cardiology·Marco Guazzi, Ross Arena
Sep 24, 2014·The Open Cardiovascular Medicine Journal·Christopher LabosThao Huynh
Sep 8, 2018·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Viola William, Wael El Kilany
Feb 9, 2012·Current Opinion in Cardiology·Peter R MitoffLisa M Mielniczuk

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