PMID: 9175942May 1, 1997Paper

Comparison of mortality risk: a score for very low birthweight infants

Archives of Disease in Childhood. Fetal and Neonatal Edition
R F MaierMichael Obladen

Abstract

To develop and evaluate a score which quantifies mortality risk in very low birthweight (VLBW) infants (birthweight below 1500 g) at admission to the neonatal intensive care unit. Five hundred and seventy two VLBW infants admitted from 1978 to 1987 were randomly assigned to a cohort (n = 396) for score development and a cohort (n = 176) for score validation. Two hundred and ninety four VLBW infants admitted from 1988 to 1991 were used to compare risk adjusted mortality between the two eras. Using multiple regression analysis, birthweight, Apgar score at 5 minutes, base excess at admission, severity of respiratory distress syndrome, and artificial ventilation were predictive of death in the development cohort. According to regression coefficients, a score ranging from 3 to 40 was developed. At a cutoff of 21, it predicted death in the validation cohort with a sensitivity of 0.85, a specificity of 0.73, and a correct classification rate of 0.76. The area under the receiver operating characteristic curve was 0.86. There was no significant difference in risk severity and in risk adjusted mortality between the eras 1978-87 and 1988-91. The present score is robust, easily obtainable at admission, and permits early randomisation based...Continue Reading

References

Nov 1, 1988·Critical Care Medicine·M M PollackP R Getson
Jul 1, 1988·Paediatric and Perinatal Epidemiology·C C Patterson, H L Halliday
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Jul 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·R H de Courcy-WheelerH R Gamsu
Jan 1, 1997·Archives of Disease in Childhood. Fetal and Neonatal Edition·S A Deshpande, M P Platt

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Citations

Apr 29, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·William O Tarnow-Mordi
Dec 23, 2004·Archives of Disease in Childhood. Fetal and Neonatal Edition·J S DorlingB Manktelow
Nov 26, 1998·Archives of Disease in Childhood. Fetal and Neonatal Edition·B ZernikowK H Hennecke
Feb 23, 1999·Journal of Perinatal Medicine·J HentschelM Obladen
Jun 10, 2008·The Journal of Pediatrics·Rebecca E RosenbergGary L Darmstadt
Jun 26, 2007·Seminars in Fetal & Neonatal Medicine·Elizabeth S Draper, David J Field
Apr 5, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Bhawandeep GargNazanin Farahbakhsh
Jul 29, 2005·Journal of Perinatology : Official Journal of the California Perinatal Association·Guillermo MarshallUNKNOWN Grupo Colaborativo NEOCOSUR
Apr 17, 2004·European Journal of Pediatrics·Simon J BroughtonAnne Greenough
Jun 11, 2021·Computers in Biology and Medicine·Stephanie BakerIan Atkinson

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