Comparison of MRI and 18F-FDG PET/CT in the preoperative evaluation of uterine carcinosarcoma

Gynecologic Oncology
Hyun Ju LeeJoo-Hyun Nam

Abstract

To compare the validities of magnetic resonance imaging (MRI) and (18)F-fluoro-deoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) in preoperative evaluation of uterine carcinosarcoma. Pathologic results of primary tumor lesions and paraaortic and pelvic lymph node (LN) areas were compared with the preoperative image findings. Differences in the validity parameters of both images were compared using McNemar test. For detecting primary tumor lesions (n=56), the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for (18)F-FDG PET/CT versus MRI were 98.1% versus 98.1% (P=1.000), 33.3% versus 100% (P=0.157), 94.6% versus 98.2% (P=0.500), 96.3% versus 100%, and 50% versus 75%, respectively. For paraaortic LN areas, the values were 77.8% versus 51.9% (P=0.016), 90.2% versus 100% (P=0.025), 85.9% versus 83.3% (P=0.774), 80.8% versus 100%, and 88.5% versus 79.7%, respectively. For pelvic LN areas, the values were 61.1% versus 50% (P=0.125), 86.8% versus 89.5% (P=0.727), 78.6% versus 76.8% (P=0.774), 68.8% versus 69.2%, and 82.5% versus 79.1%, respectively. For extrauterine disease, the patient-based values for (18)F-FDG PET/CT were 100%, 78.9%, 85.7%, 69.2%, and 100...Continue Reading

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Citations

Jul 13, 2018·The Journal of International Medical Research·Jiang-Tao ZhongHe-Ming Han
Sep 20, 2016·Obstetrical & Gynecological Survey·Jorge Daniel Oldan, Parth S Patel
Dec 13, 2018·Nuclear Medicine and Molecular Imaging·Soyoung KimWon Jun Kang
Apr 29, 2019·Abdominal Radiology·Pavitra RavishankarNikhil H Ramaiya
Jul 8, 2020·World Journal of Surgical Oncology·Aparna SetiaVaruna Mallya
Sep 5, 2020·Case Reports in Obstetrics and Gynecology·Ali KordKaren L Xie
Jan 11, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yu-Ting HuangGigin Lin
Oct 18, 2019·Seminars in Cancer Biology·Holly E Barker, Clare L Scott
Mar 9, 2021·The British Journal of Radiology·Janette SmithHelen Clare Addley

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