Comparison of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy With Systematic Biopsy Alone for the Diagnosis of Prostate Cancer: A Systematic Review and Meta-analysis

JAMA Network Open
Martha M C ElwenspoekPenny Whiting

Abstract

The current diagnostic pathway for patients with suspected prostate cancer (PCa) includes prostate biopsy. A large proportion of individuals who undergo biopsy have either no PCa or low-risk disease that does not require treatment. Unnecessary biopsies may potentially be avoided with prebiopsy imaging. To compare the performance of systematic transrectal ultrasonography-guided prostate biopsy vs prebiopsy biparametric or multiparametric magnetic resonance imaging (MRI) followed by targeted biopsy with or without systematic biopsy. MEDLINE, Embase, Cochrane, Web of Science, clinical trial registries, and reference lists of recent reviews were searched through December 2018 for randomized clinical trials using the terms "prostate cancer" and "MRI." Randomized clinical trials comparing diagnostic pathways including prebiopsy MRI vs systematic transrectal ultrasonography-guided biopsy in biopsy-naive men with a clinical suspicion of PCa. Data were pooled using random-effects meta-analysis. Risk of bias was assessed using the revised Cochrane tool. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed. All review stages were conducted by 2 reviewers. Detection rate of clinically signifi...Continue Reading

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Citations

Aug 8, 2019·JAMA Network Open·Peter C Albertsen
Dec 14, 2019·Der Radiologe·Attila Kovács, Michael Pinkawa
Mar 21, 2020·Current Opinion in Oncology·Mohammad Amin HadavandMohummad Minhaj Siddiqui
Feb 6, 2020·Topics in Magnetic Resonance Imaging : TMRI·Ryan D Ward, Andrei S Purysko
Oct 24, 2019·Current Opinion in Urology·Joseph M NorrisVeeru Kasivisvanathan
Feb 12, 2021·Asian Journal of Urology·Kulthe Ramesh Seetharam BhatAnanthakrishnan Sivaraman
Feb 14, 2021·Proteomics. Clinical Applications·Venera Kuci EmruliCarl A K Borrebaeck
May 10, 2021·Current Opinion in Urology·Pascal A T Baltzer, Paola Clauser
Aug 7, 2021·The British Journal of Radiology·Simona IppolitiTristan Barrett

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

Stata
RoB

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