Comparison of multislice computed tomography to gated single-photon emission computed tomography for imaging of healed myocardial infarcts

The American Journal of Cardiology
M M HennemanJeroen J Bax

Abstract

The aim of the study was to evaluate the performance of multislice computed tomography (MSCT) for the detection and semiquantitative analysis of healed myocardial infarct in comparison to single-photon emission computed tomography (SPECT). Recently, MSCT was shown to allow detection of myocardial infarct by the presence of hypoenhanced areas. However, direct comparisons to other imaging modalities for infarct imaging were scarce. In 69 patients with healed myocardial infarct (>3 months), the presence of myocardial infarct and infarct score was assessed using SPECT and MSCT. In addition, regional and global left ventricular function was assessed using MSCT. In 62 of 69 patients (90%), a perfusion defect was detected using gated SPECT at rest. Using MSCT in these 62 patients (100%), hypoenhanced areas reflecting infarct were shown. In 3 of 7 patients (43%) without perfusion defects who underwent gated SPECT, MSCT identified regions of infarct. The infarct score on MSCT related well to the SPECT infarct score (12 +/- 10% vs 16 +/- 13%; r = 0.93, p <0.0001). In addition, good (inverse) correlations were shown for infarct score using MSCT and parameters of left ventricular function. In conclusion, healed myocardial infarct can be de...Continue Reading

References

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Citations

Feb 24, 2012·AJR. American Journal of Roentgenology·Rozemarijn VliegenthartU Joseph Schoepf
Dec 21, 2013·Radiology·Alexia RossiGabriel P Krestin
May 25, 2011·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·J G J GroothuisA C van Rossum
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Jul 18, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Andreas K BuckAlexander Drzezga

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