PMID: 16511788Mar 3, 2006Paper

Comparison of Multistix PRO dipsticks with other biochemical assays for determining urine protein (UP), urine creatinine (UC) and UP:UC ratio in dogs and cats

Veterinary Clinical Pathology
Elizabeth G WellesJames C Wright

Abstract

Urine protein: urine creatinine (UP:UC) ratio determined from the quantitative measurement of protein and creatinine in a single urine sample is the best feasible assessment of clinically significant proteinuria in dogs and cats. A dipstick that measures urine protein, urine creatinine, and UP:UC ratio has been used in human medicine and could have application for veterinary practice. The objective of this study was to compare the Multistix PRO dipstick (Bayer Corporation, Elkhart, IN, USA) to other biochemical methods for determination of urine protein and creatinine, and UP:UC ratio in canine and feline urine. A complete urinalysis, including sulfosalicylic acid (SSA) precipitation, was performed on urine samples submitted to our laboratory between February and April 2003 from 100 dogs and 49 cats. Urine protein and creatinine concentrations were determined by the Multistix PRO dipstick using a Clinitek 50 analyzer (Bayer) and compared with the results of SSA precipitation and quantitative biochemical analysis. The UP:UC ratios from the dipstick results (calculated by the Clinitek 50 and also manually) were compared with those calculated from quantitative values. Pearson product-moment correlation analysis and diagnostic sens...Continue Reading

Citations

Jan 31, 2013·Research in Veterinary Science·M DefontisA Moritz
Feb 25, 2009·Journal of Feline Medicine and Surgery·Harriet M Syme
Mar 5, 2016·Journal of Feline Medicine and Surgery·George Reppas, Susan F Foster
Oct 31, 2018·Journal of Animal Physiology and Animal Nutrition·Florian Karl ZeugswetterIlse Schwendenwein
Jun 2, 2018·The Veterinary Record·Marisa da Fonseca FerreiraAdam George Gow
Jul 17, 2014·Journal of the American Animal Hospital Association·Christina MamoneMark Acierno
Jul 28, 2020·Journal of the American Veterinary Medical Association·Caroline F AldridgeHollie P Lee
Feb 2, 2021·Journal of Veterinary Science·Sumin JiYongbaek Kim
Jan 22, 2011·The Veterinary Clinics of North America. Small Animal Practice·Meryl P Littman

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