PMID: 6138924Feb 1, 1982

Comparison of nitrazepam with triazolam in insomniac outpatients

Acta Psychiatrica Scandinavica
L E DahlH Kullingsjö

Abstract

The short-acting hypnotic, triazolam 0.5 mg, was compared in a 7-day double-blind study with the longer acting drug, nitrazepam 5 mg. Of the 60 patients enrolled, 29 in each drug treatment group completed the study and were evaluated. All significant differences found favoured triazolam. On the first night, triazolam was found to be significantly more effective than nitrazepam in inducing and maintaining sleep and in increasing its overall duration. The patients' subjective preference, reflecting the depth of sleep experienced and the effect of the medication, reached highly significant levels in favour of triazolam. Later in the study the differences between the drugs disappeared although the depth of sleep as judged in the study was better with triazolam.

References

Jan 1, 1976·The Journal of International Medical Research·T RothT Lutz
Apr 17, 1979·European Journal of Clinical Pharmacology·L KangasE Syvälahti
Jan 1, 1972·Psychopharmacologia·A J Bond, M H Lader
Feb 1, 1980·British Journal of Clinical Pharmacology·A N Nicholson, B M Stone
Jan 1, 1981·Clinical Pharmacology and Therapeutics·F S EbertsR W Vliek
Mar 15, 1980·British Medical Journal

Citations

Sep 16, 1989·Lancet·R F Drucker, N MacLeod
Jan 1, 1990·Journal of Psychoactive Drugs·V L Martin
Jan 1, 1984·Current Medical Research and Opinion·R BanderaS Garattini

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