Comparison of non-invasive tear film stability measurement techniques

Clinical & Experimental Optometry : Journal of the Australian Optometrical Association
Michael T M WangJennifer P Craig

Abstract

Measurement of tear film stability is commonly used to give an indication of tear film quality but a number of non-invasive techniques exists within the clinical setting. This study sought to compare three non-invasive tear film stability measurement techniques: instrument-mounted wide-field white light clinical interferometry, instrument-mounted keratoscopy and hand-held keratoscopy. Twenty-two subjects were recruited in a prospective, randomised, masked, cross-over study. Tear film break-up or thinning time was measured non-invasively by independent experienced examiners, with each of the three devices, in a randomised order, within an hour. Significant correlation was observed between instrument-mounted interferometric and keratoscopic measurements (p < 0.001) but not between the hand-held device and the instrument-mounted techniques (all p > 0.05). Tear film stability values obtained from the hand-held device were significantly shorter and demonstrated narrower spread than the other two instruments (all p < 0.05), while no significant differences were observed between the two instrument-mounted devices (all p > 0.05). Good clinical agreement exists between the instrument-mounted interferometric and keratoscopic measurements...Continue Reading

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Citations

Oct 23, 2019·Translational Vision Science & Technology·Louis TongRyan Khee Jin Lee
May 3, 2019·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Clara Llorens-QuintanaD Robert Iskander
Apr 29, 2020·Topics in Stroke Rehabilitation·Esin Benli KüçükGamze Yıldırım Biçer
Sep 14, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Joevy LimJennifer P Craig
Feb 16, 2021·Journal français d'ophtalmologie·P-E RemonginM Labetoulle
Jan 23, 2021·Journal of Optometry·Jesús VeraRaimundo Jiménez
May 19, 2021·Translational Vision Science & Technology·Eisuke ShimizuKazuo Tsubota

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