PMID: 16633223Apr 25, 2006Paper

Comparison of objective diagnostic tests in glaucoma: Heidelberg retinal tomography and multifocal visual evoked potentials

Journal of Glaucoma
C BalachandranIvan Goldberg

Abstract

To compare sensitivity and specificity of functional and structural changes in glaucoma using two objective tests: the multifocal visual evoked potential (m-VEP) and Heidelberg retinal tomography II (HRT). 41 glaucoma patients and 25 normal individuals participated in the study. One eye per individual was included in the study. Individuals were evaluated with Humphrey visual field (HVF) perimetry, m-VEP, and HRT. Moorfield regression analysis findings of HRT were compared with presence of scotoma on m-VEP. Linear regression analysis of quantitative variables, such as HVF mean deviation (MD), m-VEP discriminant score (Accumap Severity Index) and, global HRT parameters was also performed. m-VEP sensitivity and specificity were 93% and 96% respectively. HRT sensitivity and specificity were 79% and 92% respectively. The area under the receiver operating characteristic curve (ROC) for m-VEP was 0.96 and for HRT varied from 0.79 to 0.86 depending on the parameters used. Linear correlation between MD and Accumap Severity Index score was -77%, while that between HRT global parameters, Accumap Severity Index and MD were at best around 50%. Topographic comparison of the presence of scotoma on HVF and m-VEP in different areas of the visua...Continue Reading

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Citations

Jun 10, 2010·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A SteindelH G Struck
Sep 10, 2008·Documenta Ophthalmologica. Advances in Ophthalmology·Alexander KlistornerC Yiannikas
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Sep 8, 2010·Documenta Ophthalmologica. Advances in Ophthalmology·Manju JayaramanParveen Sen
Jul 8, 2011·Documenta Ophthalmologica. Advances in Ophthalmology·Carlos Gustavo De MoraesDonald C Hood
Aug 20, 2011·Documenta Ophthalmologica. Advances in Ophthalmology·Makoto NakamuraAkira Negi
Mar 13, 2014·Documenta Ophthalmologica. Advances in Ophthalmology·Makoto NakamuraTakayuki Nagai
May 13, 2011·Journal of Glaucoma·Tiago Santos PrataCelso Tello
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Apr 12, 2018·Asia-Pacific Journal of Ophthalmology·Tak Yee Tania Tai
Oct 19, 2019·Documenta Ophthalmologica. Advances in Ophthalmology·Mathias Falck SchmidtJette Lautrup Frederiksen
Jul 14, 2017·Documenta Ophthalmologica. Advances in Ophthalmology·Li Juan XuYuan Bo Liang
Feb 18, 2011·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Henry Ho-Lung ChanPatrick Ho-wai Chu

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