Comparison of Obstetric Outcomes of Pregnancies after Donor-Oocyte In vitro Fertilization and Self-Oocyte In vitro Fertilization: A Retrospective Cohort Study

Journal of Human Reproductive Sciences
Vikas YadavAlka Kriplani

Abstract

The aim of this study is to evaluate and compare multiple obstetric and perinatal outcomes between donor-oocyte in vitro fertilization (IVF) and self-oocyte IVF group. This study was done in a tertiary care center with ART unit. This was a retrospective comparative cohort study. The present study comprised all women between 20 and 45 years who conceived from oocyte donation (n = 78) between December 1, 2010, and December 31, 2016, and compared with all women who underwent self-oocyte IVF (n = 112). The process involved controlled ovarian stimulation and retrieval of the donor oocytes, preparation of recipient endometrium, and pregnancy management. Obstetric and perinatal outcomes were compared. Chi-square test was used for categorical variables. Analysis for confounding variables was performed using multivariable linear and logistic regression analysis. Baseline characteristics between the two groups were comparable. Miscarriage, first-trimester bleeding, pregnancy-induced hypertension (PIH), and gestational diabetes mellitus were significantly higher in donor-oocyte IVF group compared to self-oocyte cycles (P = 0.001). Using multiple logistic regression analysis, age class adjusted PIH incidence was significantly higher in don...Continue Reading

References

Mar 25, 2014·American Journal of Obstetrics and Gynecology·Yacov LevronYoav Yinon

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Citations

Apr 6, 2021·Zygote : the Biology of Gametes and Early Embryos·Romualdo SciorioBruno Engl
Jun 19, 2021·Pregnancy Hypertension·Maya RamYariv Yogev

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Methods Mentioned

BETA
pregnancy test
cesarean section

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