Abstract
To evaluate ocular findings during the pandemic influenza A (H1N1) and after vaccination for the same strain. This study was conducted on 89 patients with H1N1 influenza infection (group 1) and 28 subjects who received vaccination for H1N1 (group 2). All patients were subjected to history taking, ophthalmological examination, fundus examination, conjunctival impression cytology and conjunctival swabs. The patients' age ranged between 5 and 60 years (19.25 ± 11.70 years). Group 1 included 43 (48.1%) males and 46 (51.9%) females, while group 2 included 13 (46.43%) males and 15 (53.57%) females. The most common ocular finding of patients in group 1 was bilateral acute conjunctivitis in 58 cases (65.17%), while in group 2, we found 3 (10.71%) cases of mild conjunctivitis, and 2 (7.14%) cases of moderate conjunctivitis. Retinopathy, uveal affection, and optic neuritis were not statistically different between the 2 groups. Impression cytology of the conjunctiva for group 1 showed squamous metaplasia grade 3 with enlargement of epithelial cells, and fragmentation of the nucleus which is similar to virus-infected structural changes. Pandemic influenza H1N1 was able to induce different ocular manifestations including acute conjunctiviti...Continue Reading
References
Mar 1, 1993·Survey of Ophthalmology·S L YoserN A Rao
Dec 21, 2006·Japanese Journal of Ophthalmology·Teitei JoMinoru Tanaka
Nov 4, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·William HuynhChris Dedousis
May 16, 2009·Microbes and Infection·Nadia Naffakh, Sylvie van der Werf
May 22, 2009·Journal of Virology·Jessica A BelserTerrence M Tumpey
Jun 16, 2009·Biologicals : Journal of the International Association of Biological Standardization· Who
Jun 26, 2009·Investigative Ophthalmology & Visual Science·Martin MichaelisJindrich Cinatl
Aug 1, 2009·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·N KomiyaN Okabe
Aug 5, 2009·Paediatric Respiratory Reviews·Dominic A Fitzgerald
Oct 6, 2009·Indian Journal of Pediatrics·Meghna R SebastianS K Kabra
Dec 17, 2009·The New England Journal of Medicine·Bin CaoUNKNOWN National Influenza A Pandemic (H1N1) 2009 Clinical Investigation Group of China
Dec 26, 2009·Vaccine·François RomanJeanne-Marie Devaster
Jan 30, 2010·The American Journal of Pathology·Michael C W ChanJoseph S M Peiris
Feb 27, 2010·QJM : Monthly Journal of the Association of Physicians·Y P MuH Z Lu
Aug 6, 2010·The Pediatric Infectious Disease Journal·Keswadee LapphraDavid W Scheifele
Aug 17, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Kyoung Yul SeoMi-Na Kweon
Citations
Aug 3, 2012·Journal of Virology·Laurence JossetIlhem Messaoudi
Mar 9, 2013·Microbiology and Molecular Biology Reviews : MMBR·Jessica A BelserTerrence M Tumpey
May 21, 2013·Virus Research·Renee W Y ChanJ S Malik Peiris
Jul 6, 2015·Virology·Jessica A BelserTerrence M Tumpey
Jan 31, 2015·Virulence·E M Abdelwhab, Ahmed S Abdel-Moneim
Jul 1, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T Ness, H Hengel
Dec 22, 2012·Ophthalmic Research·Moncef KhairallahRiadh Messaoud
Jan 16, 2015·PLoS Neglected Tropical Diseases·Sasha R FehilyAndrew J Fuller
Nov 13, 2013·Innate Immunity·Shweta TripathiKevan L Hartshorn
Aug 15, 2017·Viruses·Jung Min ShimDenis E Kainov
Sep 28, 2017·Viruses·Daria BulanovaDenis E Kainov
Sep 14, 2013·Current Opinion in Ophthalmology·Moncef Khairallah, Rim Kahloun
Jun 25, 2015·Asia-Pacific Journal of Ophthalmology·Ratnesh Ranjan, Shikha Ranjan
Jun 17, 2014·Internal Medicine·Jiro FujitaMasao Tateyama
Jul 27, 2017·Influenza and Other Respiratory Viruses·Subhashini A SellersWilliam A Fischer
Nov 26, 2014·Retinal Cases & Brief Reports·Albert Y CheungGeorge A Williams
Mar 12, 2020·Ocular Immunology and Inflammation·Leonardo Ferreira JorgeDaniel Vítor Vasconcelos-Santos
Sep 25, 2020·Current Opinion in Ophthalmology·Veronica Kon GraversenTimothy G Murray
Jan 11, 2021·Journal of Optometry·Rebika DhimanRohit Saxena
Jan 31, 2021·Eye·Ashwin VenkateshParwez Hossain
Jan 30, 2021·World Journal of Radiology·Azadeh EslambolchiAli Gholamrezanezhad
Oct 4, 2020·Current Opinion in Ophthalmology·Veronica Kon GraversenTimothy G Murray