Comparison of Optical Coherence Tomography Measurement Reproducibility between Children and Adults

PloS One
Ho Kyung ChungSeok Hwan Kim

Abstract

To compare the reproducibility of SD-OCT (spectral-domain optical coherence tomography) measurements of RNFL (retinal nerve fiber layer) and macular thickness between children and adults. Seventy-one eyes of 71 children and 71 eyes of 71 adults were prospectively enrolled. RNFL and macular thicknesses were measured by one operator, with a brief rest between measurements. The two measurements were obtained using the eye tracking and retest function of Spectralis SD-OCT. Reproducibility was evaluated with reference to COVs (coefficients of variation) and ICCs (intraclass correlation coefficients). The ICC values of the RNFL and macular thicknesses were compared, respectively between the two groups, by Fisher's z-test. The RNFL and macular thicknesses did not differ between the two groups. The COVs of the RNFL measurements ranged from 0.945 to 4.531% in the children group and from 0.496 to 1.391% in the adults group. In most of the RNFL sectors, the ICCs of the children group (range: 0.731-0.987) were significantly lower than those of the adults group (range: 0.986-0.993). The COVs of the macular measurements ranged from 0.496 to 1.157% in the children group and from 0.275 to 0.656% in the adults group. The ICCs (range: 0.860-0.97...Continue Reading

References

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Citations

Sep 28, 2018·Acta Ophthalmologica·Bohdan KousalPetra Liskova
Apr 15, 2020·Journal of Glaucoma·Samantha Sze-Yee LeeDavid A Mackey
Jun 2, 2018·International Journal of Endocrinology·P Ruiz-OcañaA M Lechuga-Sancho
Aug 4, 2020·European Journal of Ophthalmology·Maria Jiménez SantosRosario Gómez de Liaño
May 19, 2021·Translational Vision Science & Technology·Samantha Sze-Yee LeeDavid Anthony Mackey
Aug 4, 2021·Translational Vision Science & Technology·Gareth LinghamDavid A Mackey

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Methods Mentioned

BETA
imaging technique

Software Mentioned

OCT
SPSS
Spectralis
SD
R
Spectralis SD - OCT
Spectralis OCT
Heidelberg Spectralis OCT
Statistical Package for the Social Sciences
R Foundation for

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