Comparison of optimized long echo time STEAM and PRESS proton MR spectroscopy of lipid olefinic protons at 3 Tesla

Journal of Magnetic Resonance Imaging : JMRI
Ayhan BingölbaliAtiyah Yahya

Abstract

To investigate the response of lipid olefinic protons (≈ 5.35 ppm) as a function of STEAM (Stimulated Echo Acquisition Mode) mixing time (TM), and echo time (TE), to find values that resolve the olefinic resonance from water in vivo while retaining sufficient olefinic signal. PRESS (Point RESolved Spectroscopy) and STEAM experiments with varying timing parameters (TE and also TM for STEAM) were conducted on nine oils (almond, canola, cod liver, corn, linseed, peanut, sesame, sunflower, and walnut oil), and on vertebral bone marrow in vivo at 3 Tesla (T). Olefinic and methylene (methyl + methylene in vivo) peak areas were measured. Optimal STEAM parameters were found to be TM = 20 ms and TE = 100 ms. The STEAM olefinic/methylene area ratios (ranging between 0.1 and 0.4) calculated for each oil correlated well with ratios deduced from oil compositions in the literature (R(2)  = 0.975). The optimized STEAM sequence resolved the olefinic peak from water in vivo and yielded on average 1.91 times more olefinic signal compared with a previously optimized PRESS (TE = 200 ms) sequence tailored for the same purpose. Olefinic/(methyl + methylene) area ratios obtained with optimized STEAM and PRESS in vivo were linearly correlated (R(2)  =...Continue Reading

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Citations

Mar 11, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Stefan RuschkeDimitrios C Karampinos
Jul 23, 2016·Frontiers in Endocrinology·Christian CordesDimitrios C Karampinos
Jun 2, 2017·Journal of Magnetic Resonance Imaging : JMRI·Dimitrios C KarampinosThomas Baum
Dec 12, 2017·Journal of Magnetic Resonance Imaging : JMRI·Clara J FalloneAtiyah Yahya
Oct 31, 2018·NMR in Biomedicine·Logan Fairgrieve-ParkAtiyah Yahya
Aug 13, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jan SyväriDimitrios C Karampinos
Mar 2, 2017·Journal of Biomedical Science·Oun Al-IedaniSaadallah Ramadan
Mar 3, 2021·Best Practice & Research. Clinical Endocrinology & Metabolism·Mohamed Jarraya, Miriam A Bredella

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