Comparison of oral lesion prevalence in renal transplant patients under immunosuppressive therapy and healthy controls

Oral Diseases
Rosa María López-PintorAmado de Andrés

Abstract

The aim of this study was to analyse the prevalence of oral lesions in a group of renal transplant patients (RTPs) compared with healthy controls (HCs). The study included 500 RTPs (307 men, 193 women, mean age 53.63 years) and 501 HCs (314 men, 187 women, mean age 52.25 years). Demographic and pharmacologic data were recorded for all subjects. Forty percent of the RTPs presented with oral lesions compared to 23.4% of HCs. The most frequent lesion was candidiasis (7.4% in RTPs, 4.19% in HCs). Lip herpes simplex lesions were observed in 2.6% of RTPs and 2.2% of HCs; aphthae were observed in 2.2% of RTPs and 1% of HCs. Xerostomia prevalence was significantly greater in RTPs than HCs (1.4%vs 0.2%). Lichen planus appeared in 0.6% of RTPs, and one RTP suffered from hairy leukoplakia. We report a lower prevalence of oral candidiasis and hairy leukoplakia in RTPs than previous reports and describe other oral conditions not presented before in prevalence studies of RTPs, such as xerostomia, aphthous ulcers and lichen planus. These oral lesion changes in RTPs and the risk of malignancy emphasize the importance of regular oral screening in these patients.

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Citations

Mar 1, 2012·Journal of Transplantation·Gonzalo RojasIrene Morales
Feb 7, 2013·Medicina oral, patología oral y cirugía bucal·Rosa-María López-PintorAmado de Andrés
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Related Concepts

Immunosuppressive Agents
Mouth Diseases
Logistic Regression
Nested Case-Control Studies
Kidney Transplantation
Malignant Neoplasms
Candidiasis
Oral Candidiasis
Therapeutic Immunosuppression
Lichen - organism

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