Comparison of Ozone and Photo-Biomodulation Therapies on Mental Nerve Injury in Rats

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Turker YucesoyAlper Alkan

Abstract

This study compared photo-biomodulation (PBM) and ozone therapy (OT) for mental nerve injury by counting Schwann cells (SCs) and fasciculated nerve branches and measuring fascicular nerve areas. The effects of OT and PBM on mental nerve injury were evaluated. Mental nerves of 27 rats were partly sutured and allocated into 3 groups. Group 1 received no treatment, group 2 received OT, and group 3 received PBM. The number of fascicules beyond nerve branches and the number of SCs before and after nerve injury were evaluated histologically. A better healing pattern was observed in the treatment groups. The number of SCs was markedly larger in the OT and PBM groups than in the control group. Oral and maxillofacial surgeons should be familiar with the differential diagnosis, prevention, and management of neurosensory disturbances. This study provides insights into the management of neurosensory disturbances related to mental nerve injury using OT and PBM. This study clearly suggests that OT and PBM are promising novel methods for the treatment of mental nerve injury.

References

Mar 1, 1993·Neurotoxicology and Teratology·D SantucciE Alleva
Jan 18, 2006·International Journal of Biological Macromolecules·V Bocci, V Travagli

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Citations

Feb 18, 2020·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Yusuf YucaAlper Alkan
May 1, 2021·International Journal of Molecular Sciences·Silvia RaveraAndrea Amaroli

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