Comparison of Pain Within 24 h after Uterine Artery Embolization with Tris-Acryl Gelatin Microspheres Versus Gelatin Sponge Particles for Leiomyoma

Cardiovascular and Interventional Radiology
Tetsuya KatsumoriHiroshi Miura

Abstract

To compare acute pain after uterine artery embolization (UAE) with tris-acryl gelatin microspheres (TAGM) versus gelatin sponge particles (GS) for leiomyoma. This was a single-institution, retrospective study. Between July 2008 and November 2016, 101 consecutive patients with symptomatic uterine leiomyoma underwent UAE with the same protocol for post-procedural pain. GS was employed with near-stasis endpoint for the first 49 patients, whereas TAGM was used with limited endpoint for the next 52 patients. Post-UAE pain levels were compared between both groups with a linear mixed model using visual analog scale (VAS) scores from 0 to 18 h as a repeat measure outcome. Peak VAS < 24 h or dose of drugs for analgesia and conscious sedation was compared by analysis of variance. Tumor infarction was assessed with post-procedural contrast-enhanced MRI. Baseline demographics and most outcomes including tumor infarction were similar between both groups. The average VAS scores during the period <24 h were significantly lower in TAGM group (1.68, 95% CI 1.23-2.13) compared to GS group (3.28, 95% CI 2.82-3.74, p < 0.0001). The difference remained significant even after adjustment for other factors (p < 0.0001). The mean peak VAS < 24 h was al...Continue Reading

References

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Citations

Sep 15, 2019·Cardiovascular and Interventional Radiology·Affan SaibudeenRaman Uberoi
Nov 12, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Shudong Liu, Wenyan Li
Mar 2, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Zuoxiang DongChangjiang Fan

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