Comparison of percutaneous transluminal septal myocardial ablation versus septal myectomy for the treatment of patients with hypertrophic obstructive cardiomyopathy--a meta analysis

International Journal of Cardiology
Zhiyu ZengJielin Pu

Abstract

The effects of percutaneous transluminal septal myocardial ablation (PTSMA) with septal myectomy in patients with hypertrophic obstructive cardiomyopathy (HOCM) are not thoroughly compared. Three articles comparing the effects of PTSMA and septal myectomy treatment for HOCM were identified from a search in Pubmed, and a meta analysis was conducted. 177 patients (86 underwent PTSMA and 91 underwent septal myectomy) were included. Interventricular septum thickness was decreased from 22.1 to 15.1 mm (p<0.05) in PTSMA group and from 22.0 to 13.9 mm (p<0.05) in septal myectomy group; left ventricular end-diastolic dimension was increased from 41.8 to 45.2 mm (p<0.05) in PTSMA group and from 41.8 to 43.9 mm (p<0.05) in septal myectomy group; NYHA class was improved from 3.17 to 1.47 (p<0.05) in PTSMA group and from 2.97 to 1.36 (p<0.05) in septal myectomy group; there were no differences in the two groups. However, left ventricular outflow tract gradient was decreased from 76.0 to 15.7 mm Hg (p<0.05) in PTSMA group and from 74.7 to 9.4 mm Hg (p<0.05) in septal myectomy group and the effect of septal myectomy was better than PTSMA (p<0.05). The effects of septal myectomy treatment for HOCM are better with regard to relief of LVOT grad...Continue Reading

Citations

Dec 13, 2017·Journal of Clinical Medicine·Alphonsus C LiewClaire E Raphael
May 18, 2012·The Cochrane Database of Systematic Reviews·Mohammed QintarWaleed Kadro
Aug 24, 2018·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Farah N MusharbashRalph J Damiano
Jul 15, 2015·Current Opinion in Cardiology·Bogdan A PopescuEhud Schwammenthal

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