PMID: 6408141Jul 1, 1983Paper

Comparison of Phadebact coagglutination tests with counterimmunoelectrophoresis for the detection of bacterial antigens in cerebrospinal fluid

Journal of Clinical Pathology
D S Tompkins

Abstract

One hundred and seventeen specimens of cerebrospinal fluid from 94 patients were examined for the presence of pneumococcal and Haemophilus influenzae type b antigens using counterimmunoelectrophoresis and coagglutination tests. The coagglutination method using Phadebact reagents was as sensitive as counterimmunoelectrophoresis, but culture was a more sensitive diagnostic procedure than either test. A meningococcus coagglutination reagent, included in a prototype meningitis diagnostic kit, was also found to be as sensitive as counterimmunoelectrophoresis when tested on culture-positive cerebrospinal fluid specimens. Coagglutination tests for the detection of bacterial antigen are useful supportive tests when used in conjunction with direct microscopy and culture for bacterial pathogens.

References

Jul 1, 1978·American Journal of Diseases of Children·W E Feldman
Oct 1, 1974·The Journal of Pediatrics·P G ShackelfordR D Feigin
Jul 1, 1972·Journal of Clinical Pathology·B M Tobin, D M Jones
Jun 1, 1981·The Journal of Infection·G D CurtisD S Tompkins
Jan 1, 1982·The Journal of Infection·M C KelseyJ M Mowles

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Citations

Jan 1, 1991·Transactions of the Royal Society of Tropical Medicine and Hygiene·J E SippelZ Farid
Nov 1, 1985·Diagnostic Microbiology and Infectious Disease·P R Murray
Nov 1, 1985·Diagnostic Microbiology and Infectious Disease·M A Gerber
Sep 1, 1985·Diagnostic Microbiology and Infectious Disease·D J HobanG W Hammond
Sep 1, 1987·Molecular and Cellular Probes·F Malouin, L E Bryan
Oct 13, 1984·British Medical Journal·R G Finch
Nov 1, 1983·Journal of Clinical Pathology·V JonesC Hart
Aug 1, 1984·Journal of Clinical Pathology·B Cookson, A Baldwin
Jan 15, 1989·American Journal of Ophthalmology·W M SobolK R Wilhelmus
Nov 1, 1986·The Journal of Infection·Y Mahida, M Noone
Nov 1, 1983·Journal of Clinical Pathology·W GillespieF Falkiner
Nov 1, 1983·Journal of Clinical Pathology·G S Gabra, R Mitchell
Apr 1, 1992·Clinical Microbiology Reviews·L D Gray, D P Fedorko

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