PMID: 3321380Jan 1, 1987Paper

Comparison of phenotype expression by mononuclear phagocytes within subcutaneous gouty tophi and rheumatoid nodules

Rheumatology International
D G PalmerP A Hessian

Abstract

The mononuclear phagocyte infiltrate which occupies the gout tophus has been compared with that of the subcutaneous rheumatoid nodule. In the gout tophus, macrophage migration appears to be at a relatively low level and effectively terminates once these cells have been recruited into the corona. In the nodule the evidence suggests that both macrophage and granulocyte populations continuously migrate towards, and are progressively incorporated into, the necrotic centres. These observations indicate that chemotactic activity in rheumatoid nodules is at a higher level than in gout tophi, or that the rheumatoid mononuclear phagocyte is more responsive to such stimuli.

References

Apr 1, 1978·Arthritis and Rheumatism·P Hasselbacher, H R Schumacher
Jul 1, 1987·Arthritis and Rheumatism·D G PalmerI Denholm
Mar 1, 1986·Molecular Immunology·J M WoofD R Burton
Nov 20, 1982·Lancet·S A RaeM J Smith
Nov 1, 1983·Arthritis and Rheumatism·E HedforsG Lindahl
Aug 1, 1983·Annals of the Rheumatic Diseases·J J Rasker, F C Kuipers
Jun 1, 1984·The Journal of Clinical Investigation·R TerkeltaubM H Ginsberg
Sep 1, 1964·Annals of the Rheumatic Diseases·W COCHRANEE G BYWATERS

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Citations

Jan 11, 2012·Nature Reviews. Rheumatology·Fiona M McQueenNicola Dalbeth
Nov 17, 2011·Arthritis Research & Therapy·Fiona M McQueenNicola Dalbeth
Apr 19, 2000·Archives of Histology and Cytology·T IwanagaK Nozawa-Inoue
Apr 16, 2013·Arthritis·Gandikota GirishDavid A Jamadar
Feb 5, 2010·Arthritis and Rheumatism·Nicola DalbethJillian Cornish
Mar 13, 2015·Current Rheumatology Reports·Ashika Chhana, Nicola Dalbeth
Dec 18, 2013·Seminars in Arthritis and Rheumatism·Ralph MelzerBernhard Krauss
Apr 3, 2019·BMC Musculoskeletal Disorders·Patapong TowiwatNicola Dalbeth

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