Comparison of physiological and radiological screening for lung volume reduction surgery

American Journal of Respiratory and Critical Care Medicine
E P IngenitoJ J Reilly

Abstract

Physiological and radiological criteria are both used to identify candidates for LVRS. This study compares the predictive value of these screening techniques among patients with homogeneous (Ho) and heterogeneous (He) emphysema. Preoperative inspiratory lung conductance (G(Li)) during spontaneous breathing and quantitative radioisotope V/Q scan (QVQS) results were available for 48 of 50 patients undergoing bilateral LVRS for emphysema. Ho disease (n = 21) was defined by QVQS as an upper/lower perfusion ratio (ULPR) between 0.75 and1.25. G(Li) correlated with 6-mo improvement in FEV(1) (DeltaFEV(1)-6) (r = 0.53, p < 0.001) for the entire cohort, and for patients with both Ho (n = 21, r = 0.56, p = 0.015) and He disease (n = 27, r = 0.46, p = 0.017). ULPR correlated less well with DeltaFEV(1)-6 (n = 48, r = -0.38; p = 0.008) for the cohort, and was significantly correlated with outcomes only in the subgroup of patients with He disease (r = -0.40, p = 0.04). Multivariate regression demonstrated that by combining G(Li) and ULPR criteria, 33% of the DeltaFEV(1)-6 response could be accounted for. We conclude that both physiological and radiological criteria help identify appropriate candidates for LVRS. G(Li) best identifies patients...Continue Reading

References

Jan 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·J D CooperC L Roper
Oct 1, 1996·American Journal of Respiratory and Critical Care Medicine·A F GelbM Brenner
Feb 1, 1997·American Journal of Respiratory and Critical Care Medicine·F G Hoppin
Jul 1, 1997·Journal of the American College of Surgeons·S J SwansonD J Sugarbaker
Jan 22, 1998·The Journal of Thoracic and Cardiovascular Surgery·R J McKennaK E Osann
Mar 27, 1998·Chest·M BrennerA F Wilson
Mar 28, 1998·American Journal of Respiratory and Critical Care Medicine·H E Fessler, S Permutt

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Citations

May 22, 2003·The New England Journal of Medicine·Alfred FishmanUNKNOWN National Emphysema Treatment Trial Research Group
Oct 13, 2001·The New England Journal of Medicine·UNKNOWN National Emphysema Treatment Trial Research GroupRobert Wise
Jan 4, 2005·Respiration; International Review of Thoracic Diseases·Konrad E BlochErich W Russi
Dec 26, 2001·American Journal of Respiratory and Critical Care Medicine·P A Gevenois, M Estenne
Feb 19, 2002·American Journal of Respiratory and Critical Care Medicine·Tommaso C MineoNatalia Magliocchetti
Aug 20, 2005·American Journal of Respiratory and Critical Care Medicine·Robert B GormanSimon C Gandevia
Dec 8, 2009·American Journal of Respiratory and Critical Care Medicine·George R WashkoUNKNOWN National Emphysema Treatment Trial Research Group
Jun 12, 2010·American Journal of Respiratory and Critical Care Medicine·Divay ChandraUNKNOWN National Emphysema Treatment Trial Research Group
May 6, 2008·Proceedings of the American Thoracic Society·Henry E FesslerAmir Sharafkhaneh
Dec 1, 2007·International Journal of Chronic Obstructive Pulmonary Disease·Gaëlle DauriatMichel Fournier
Mar 26, 2003·Seminars in Thoracic and Cardiovascular Surgery·Konrad E BlochWalter Weder
Aug 8, 2006·The Annals of Thoracic Surgery·Keith S NaunheimUNKNOWN National Emphysema Treatment Trial Research Group
Jun 25, 2008·Chest·Bartolome R Celli
Aug 21, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Katharina MartiniThomas Frauenfelder

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