Comparison of plasma profiles of oxytocin and prolactin following suckling in the rat

Neuroendocrinology
C E GrosvenorF Mena

Abstract

The purpose of these studies was to determine the effect of suckling on the plasma oxytocin (OT) concentration profile in conscious primiparous rats during midlactation. Comparisons were made with plasma prolactin (PRL) levels obtained in the same rats. OT levels in the majority of rats exhibited a single peak during the first 5-30 min, then fell rapidly during the course of a 45-min period of suckling. The plasma OT levels were sustained over a longer period in mothers suckling 8 rather than 6 pups; the amplitudes of the OT response were similar, however. By contrast, plasma PRL profiles indicated that a steady secretion of the hormone occurred throughout the suckling period, with suckling of 8 pups resulting in significantly higher plasma levels than suckling of 6 pups. A considerably greater increase in the peak plasma OT concentration resulted when hungry foster litters of 6 pups were suckled after the mothers' own 6 pups had been suckled. Plasma PRL levels during the two sucklings, though, were similar. The rapid onset of the OT response to suckling was seen more clearly in urethane-anesthetized rats following mammary nerve stimulation. Plasma OT levels rose to a peak within 5 s after the onset, then fell to prestimulus le...Continue Reading

Citations

Nov 12, 2013·Neuropeptides·Benjamin Nephew, Chris Murgatroyd
Mar 3, 2005·Pharmacology, Biochemistry, and Behavior·Elizabeth M Byrnes
Jan 1, 1997·Brain Research Bulletin·M Juszczak, B Stempniak
Apr 1, 1992·Journal of Neuroendocrinology·L H SpinoloW R Crowley
Jun 12, 1992·Annals of the New York Academy of Sciences·M M McCarthyD W Pfaff
Aug 23, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·E JonesS A Spencer
Aug 25, 2010·Reproduction : the Official Journal of the Society for the Study of Fertility·Marcel EgliTillmann H C Kruger
Jun 12, 1992·Annals of the New York Academy of Sciences·D K SarkarN Mitsugi
Jun 12, 1992·Annals of the New York Academy of Sciences·W R CrowleyC E Grosvenor
Dec 2, 2011·Journal of Neuroendocrinology·J E Kennett, D T McKee
Sep 6, 2013·Hormones and Behavior·Lindsay M Carini, Benjamin C Nephew
Jan 7, 2017·The Journal of Experimental Biology·Eva K Fischer, Lauren A O'Connell
Sep 22, 2011·Endocrinology·Fabiana C Vilela, Alexandre Giusti-Paiva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.