Comparison of pre-existing cognitive impairment, amnesic mild cognitive impairment, and multiple domain mild cognitive impairment in men scheduled for coronary artery surgery

European Journal of Anaesthesiology
Judith A HudetzPaul S Pagel

Abstract

Preoperative cognitive impairment (PreCI), amnesic mild cognitive impairment (aMCI; a risk factor for Alzheimer's disease) and multiple domain MCI with amnesia (mdMCI+a) identify preoperative cognitive abnormalities in patients scheduled for coronary artery bypass graft surgery (CABG). Preoperative cognitive function is important in determining the incidence and severity of postoperative cognitive dysfunction, but the methods used to measure preoperative cognition are diverse. The incidence of preoperative cognitive abnormalities in cardiac surgical patients is unknown. Observational study. Veteran Administration Medical Center in the United States of America. Elective CABG surgery patients and nonsurgical controls. Recent verbal and nonverbal memory and executive functions were assessed using psychometric tests. Associations were determined using multivariate regression analysis. We quantified the incidences of PreCI, aMCI and mdMCI+a in patients before elective CABG surgery. Patients (n = 100) scheduled for surgery had lower cognitive scores compared with nonsurgical controls (n = 100) on eight of 10 psychometric tests. Differences between patients and controls were 'large' for the Immediate and Delayed Story Recall tests (Co...Continue Reading

References

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Citations

Nov 22, 2015·Brain Imaging and Behavior·Charlotte BernardIgor Sibon
Oct 13, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Wei WangFuzhou Wang
Jun 15, 2012·European Journal of Anaesthesiology·Chiara S HallerBernhard Walder
Jun 6, 2020·Mayo Clinic Proceedings·Mandeep SinghMohammed A Al-Hijji
Apr 7, 2021·British Journal of Anaesthesia·Friedrich BorchersThomas H Ottens

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