Comparison of prelaminar thickness between primary open angle glaucoma and normal tension glaucoma patients

PloS One
Youn Hea JungChan Kee Park

Abstract

The thinning of prelaminar tissue and prelamina cupping is known to occur by ischemia, as we see in anterior ischemic optic neuropathy. Since normal tension glaucoma (NTG) is thought to be more related to vascular factor than in primary open-angle glaucoma (POAG), we hypothesized that prelamina thinning may occur prominently in NTG patients. This study investigated the difference in prelaminar tissue thickness between patients with POAG and NTG and verified the factors related to prelaminar thinning. Complete ophthalmic examination including standard automatic perimetry was performed in all patients. The prelaminar tissue thickness was measured in all patients by performing enhanced depth imaging with a Heidelberg Spectralis Optical Coherence Tomography. The retinal nerve fiber layer and optic nerve head parameters were obtained using the Heidelberg Retina Tomography II and Cirrus Optical Coherence Tomography. Various ocular factors and their relationships with prelaminar thickness were analyzed. The mean prelaminar tissue thickness was significantly thinner in patients with POAG than in those with NTG. The difference in the prelaminar thickness between patients with POAG and those with NTG was greater in the early field defect...Continue Reading

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Citations

Feb 18, 2016·Asia-Pacific Journal of Ophthalmology·Ko Eun Kim, Ki-Ho Park
Aug 9, 2017·Journal of Glaucoma·Yong Woo KimKi Ho Park
Sep 15, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yengwoo SonJongyeop Park
Aug 23, 2020·Ophthalmology. Glaucoma·Shahin YazdaniMohammad Pakravan
Feb 7, 2021·Survey of Ophthalmology·Julia Corradi F AndradeTiago S Prata

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Software Mentioned

Statistical Package for the Social Sciences
Eye Explorer
SPSS
Spectralis

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