PMID: 4883848Feb 8, 1969Paper

Comparison of preseasonal and coseasonal Allpyral with Depo-Medrone in summer hay-fever

British Medical Journal
M A GandertonA W Frankland

Abstract

Three hundred patients with grass pollen hay-fever, with or without pollen asthma, were given one of three forms of treatment: preseasonal or coseasonal alum-precipitated pyridine extracted grass pollen (Allpyral) or methylprednisolone acetate in slow-release form (Depo-Medrone). Significant improvement was obtained with preseasonal Allpyral and with Depo-Medrone, but the degree of improvement obtained with coseasonal Allpyral fell within the limits of placebo response.Nevertheless, it is considered that the definite suppression of the pituitary-adrenal function which results from the use of a long-term steroid is not justified in a benign condition such as hay-fever.

References

Jan 1, 1965·International Archives of Allergy and Applied Immunology·A W Frankland
Feb 16, 1963·Lancet·B L TREADWELLW S COPEMAN
Nov 1, 1963·The Journal of Endocrinology·J LANDONV H JAMES
Jan 30, 1965·Lancet·J B WOODJ LANDON

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Citations

Jan 1, 1990·European Journal of Clinical Pharmacology·P Fell, J Brostoff
Nov 1, 1975·Archives of Disease in Childhood·P PrahlN Mygind
Jan 31, 1970·British Medical Journal·M A Ganderton, V H James
Sep 1, 1975·Clinical Allergy·G J ArcherS M Harding
Sep 1, 1976·Clinical Allergy·E J Parr
Jan 1, 1985·Statistics in Medicine·J R CharltonR Silver
Oct 28, 1999·Allergy·M AbramsonJ Weiner

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