Comparison of quantitative imaging parameters using cardiovascular magnetic resonance between cardiac amyloidosis and hypertrophic cardiomyopathy: inversion time scout versus T1 mapping

The International Journal of Cardiovascular Imaging
Bo Da NamYeon Hyeon Choe

Abstract

To compare inversion time (TI) parameters, native T1, and extracellular volume (ECV) on cardiac magnetic resonance (CMR) imaging between patients with cardiac amyloidosis (CA) or hypertrophic cardiomyopathy (HCMP). Forty six patients with biopsy-confirmed CA and 30 patients with HCMP who underwent CMR were included. T1 and TI values were measured in the septum and cavity of the left ventricle on T1 mapping and TI scout images. TI values were selected at nulling point for each myocardium and blood pool. Native T1, ECV, and TI interval values were significantly different between the CA (1170.5 ± 86.4 ms, 56.7 ± 12.2, - 11.5 ± 28.4 ms) and HCMP (1059.5 ± 63.4 ms, 28.5 ± 5.8, 66.2 ± 25.4 ms) (all p < 0.001). The diagnostic performance of the TI interval (area under the ROC curve, 0.975) was not inferior to that of the ECV (0.980, p = 0.776), and it was superior to that of the native T1 (0.845, p = 0.004). The diagnostic performance of TI interval was comparable to that of ECV for differential diagnosis between CA and HCMP. TI interval showed the feasibility as quantitative CMR parameter when T1 mapping images are not available.

References

Feb 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L D DiesbourgB O'Neill
May 14, 2003·Journal of the American College of Cardiology·James C C MoonDudley J Pennell
Sep 23, 2003·Journal of Computer Assisted Tomography·Rafaela SolerAlejandro Díaz
Jan 5, 2005·Circulation·Alicia Maria MaceiraDudley John Pennell
Jan 20, 2005·Circulation·Raymond Y Kwong, Rodney H Falk
Apr 16, 2005·European Heart Journal·Heiko MahrholdtRaymond J Kim
May 23, 2006·AJR. American Journal of Roentgenology·Rohan I vanden DriesenWendy E Strugnell
Mar 8, 2008·Journal of the American College of Cardiology·Holger VogelsbergUdo Sechtem
Feb 18, 2010·JACC. Cardiovascular Imaging·Imran S SyedMartha Grogan
Apr 25, 2012·The International Journal of Cardiovascular Imaging·Tarun PandeySanjaya Viswamitra
May 18, 2012·Circulation. Cardiovascular Imaging·Lourens F H J RobbersC Bogdan Marcu
Sep 15, 2012·JACC. Cardiovascular Imaging·François-Pierre MongeonRaymond Y Kwong
Mar 19, 2013·JACC. Cardiovascular Imaging·Theodoros D KaramitsosJames C Moon
Oct 16, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·James C MoonUNKNOWN Cardiovascular Magnetic Resonance Working Group of the European Society of Cardiology
Jan 15, 2014·JACC. Cardiovascular Imaging·Marianna FontanaJames C Moon
Nov 27, 2014·Insights Into Imaging·Rosario J PereaJoan Blade

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